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dc.contributor.author
Ramallo, Ivana Ayelen  
dc.contributor.author
González Sierra, Manuel  
dc.contributor.author
Furlan, Ricardo Luis Eugenio  
dc.date.available
2023-05-05T11:01:36Z  
dc.date.issued
2012-01  
dc.identifier.citation
Ramallo, Ivana Ayelen; González Sierra, Manuel ; Furlan, Ricardo Luis Eugenio; Discovery of β-glucosidase inhibitors from a chemically engineered extract prepared through ethanolysis; Bentham Science Publishers; Medicinal Chemistry; 8; 1; 1-2012; 112-117  
dc.identifier.issn
1573-4064  
dc.identifier.uri
http://hdl.handle.net/11336/196384  
dc.description.abstract
A series of vegetal extracts have been chemically altered by ethanolysis. The effect of the reaction on the inhibition of the enzyme β-glucosidase properties of the mixtures was studied using thin layer chromatography (TLC) with biodetection. Glucosidase inhibitory activity guided fractionation of one of the produced chemically engineered extracts led to the isolation of apigenin and ethyl p-cumarate. Both compounds were generated during the chemical modification step.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Bentham Science Publishers  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Β-GLUCOSIDASE INHIBITION  
dc.subject
CHEMICALLY ENGINEERED EXTRACTS  
dc.subject
ETHANOLYSIS  
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TLC BIODETECTION  
dc.subject.classification
Química Orgánica  
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Ciencias Químicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Discovery of β-glucosidase inhibitors from a chemically engineered extract prepared through ethanolysis  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2023-04-18T13:17:51Z  
dc.journal.volume
8  
dc.journal.number
1  
dc.journal.pagination
112-117  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Ramallo, Ivana Ayelen. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; Argentina  
dc.description.fil
Fil: González Sierra, Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina  
dc.description.fil
Fil: Furlan, Ricardo Luis Eugenio. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; Argentina  
dc.journal.title
Medicinal Chemistry  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://benthamscience.com/article/34526  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2174/157340612799278559  

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