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dc.contributor.author
Madlung, Andreas
dc.contributor.author
Masuelli, Ricardo Williams
dc.contributor.author
Watson, Brian
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Reynolds, Steve H.
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Davison, Jerry
dc.contributor.author
Comai, Luca
dc.date.available
2023-04-26T17:24:38Z
dc.date.issued
2002-06-01
dc.identifier.citation
Madlung, Andreas; Masuelli, Ricardo Williams; Watson, Brian; Reynolds, Steve H.; Davison, Jerry; et al.; Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids; Oxford University Press; Plant Physiology; 129; 2; 1-6-2002; 733-746
dc.identifier.issn
0032-0889
dc.identifier.uri
http://hdl.handle.net/11336/195500
dc.description.abstract
The joining of different genomes in allotetraploids played a major role in plant evolution, but the molecular implications of this event are poorly understood. In synthetic allotetraploids of Arabidopsis and Cardaminopsis arenosa, we previously demonstrated the occurrence of frequent gene silencing. To explore the involvement of epigenetic phenomena, we investigated the occurrence and effects of DNA methylation changes. Changes in DNA methylation patterns were more frequent in synthetic allotetraploids than in the parents. Treatment with 5-aza-2′-deoxycytidine, an inhibitor of DNA methyltransferase, resulted in the development of altered morphologies in the synthetic allotetraploids, but not in the parents. We profiled mRNAs in control and 5-aza-2′-deoxycytidine-treated parents and allotetraploids by amplified fragment length polymorphism-cDNA. We show that DNA demethylation induced and repressed two different transcriptomes. Our results are consistent with the hypothesis that synthetic allotetraploids have compromised mechanisms of epigenetic gene regulation.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Oxford University Press
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
POLYPLOIDY
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HYBRIDS
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METHYLATION
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ARABIDOPSIS
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Genética y Herencia
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2020-08-04T19:40:34Z
dc.identifier.eissn
1532-2548
dc.journal.volume
129
dc.journal.number
2
dc.journal.pagination
733-746
dc.journal.pais
Reino Unido
dc.journal.ciudad
Oxford
dc.description.fil
Fil: Madlung, Andreas. University of Washington; Estados Unidos
dc.description.fil
Fil: Masuelli, Ricardo Williams. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Biología Agrícola de Mendoza. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Instituto de Biología Agrícola de Mendoza; Argentina
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Fil: Watson, Brian. University of Washington; Estados Unidos
dc.description.fil
Fil: Reynolds, Steve H.. University of Washington; Estados Unidos
dc.description.fil
Fil: Davison, Jerry. University of Washington; Estados Unidos
dc.description.fil
Fil: Comai, Luca. University of Washington; Estados Unidos
dc.journal.title
Plant Physiology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/plphys/article/129/2/733/6110301
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1104/pp.003095
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