Artículo
Impaired mesial synchronization in temporal lobe epilepsy
Fecha de publicación:
12/2011
Editorial:
Elsevier Ireland
Revista:
Clinical Neurophysiology
ISSN:
1388-2457
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Objective: Temporal lobe epilepsy is commonly associated with synchronous, hyper-synchronous and des-synchronous activity. The aim of the present work is to explore synchronization activity in both mesial areas in temporal lobe epileptic patients during the interictal state. Methods: Using a cluster technique, we analyzed 17 temporal lobe epilepsy patients’ records of foramen ovale electrodes activity during the inter-ictal state. Results: There exists a clear tendency in the mesial area of the epileptic side to be organized as isolated clusters of electrical activity as compared with the contra-lateral side, which is organized in the form of large clusters of synchronous activity. The number of desynchronized areas is larger in the epileptic side than in the contra-lateral side in 16 out of 17 temporal lobe epileptic patients. Conclusions: The mesial area responsible for the seizures is less synchronous than the contra-lateral; the different kind of synchronous organization accounts for a lower synchronization activity at the epileptic side, suggesting that this lack of synchronous cluster organization would favour the appearance of seizures. Significance: Our results shed new light regarding synchronization issues in temporal lobe epilepsy and also it would help in reducing drastically the time of study.
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Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Articulos de SEDE CENTRAL
Citación
Ortega, Guillermo José; Peco, Iván Herrera; Sola, Rafael G.; Pastor, Jesús; Impaired mesial synchronization in temporal lobe epilepsy; Elsevier Ireland; Clinical Neurophysiology; 122; 6; 12-2011; 1106-1116
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