Artículo

Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer

Dagrosa, María AlejandraIcon ; Carpano, Marina; Perona, MarinaIcon ; Thomasz, LisaIcon ; Nievas, S.; Cabrini, R.; Juvenal, Guillermo JuanIcon ; Pisarev, Mario AlbertoIcon
Fecha de publicación: 12/2011
Editorial: Pergamon-Elsevier Science Ltd
Revista: Applied Radiation and Isotopes
ISSN: 0969-8043
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

The aim of these studies was to evaluate the possibility of treating differentiated thyroid cancer by BNCT. These carcinomas are well controlled with surgery followed by therapy with 131I; however, some patients do not respond to this treatment. BPA uptake was analyzed both in vitro and in nude mice implanted with cell lines of differentiated thyroid carcinoma. The boron intracellular concentration in the different cell lines and the biodistribution studies showed the selectivity of the BPA uptake by this kind of tumor.
Palabras clave: BPA , DIFFERENTIATED , THYROID CANCER , UPTAKE
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/188595
URL: https://www.sciencedirect.com/science/article/abs/pii/S0969804311001230
DOI: http://dx.doi.org/10.1016/j.apradiso.2011.02.030
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Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Citación
Dagrosa, María Alejandra; Carpano, Marina; Perona, Marina; Thomasz, Lisa; Nievas, S.; et al.; Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 69; 12; 12-2011; 1752-1755
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