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dc.contributor.author
Castro, Marcelo Adrian
dc.contributor.author
Yao, Jianhua
dc.contributor.author
Pang, Yuxi
dc.contributor.author
Lee, Christabel
dc.contributor.author
Baker, Eva
dc.contributor.author
Butman, John
dc.contributor.author
Evangelou, Iordanis E.
dc.contributor.author
Thomasson, David
dc.date.available
2023-02-17T19:00:49Z
dc.date.issued
2010-11
dc.identifier.citation
Castro, Marcelo Adrian; Yao, Jianhua; Pang, Yuxi; Lee, Christabel; Baker, Eva; et al.; Template-based B1 inhomogeneity correction in 3T MRI brain studies; Institute of Electrical and Electronics Engineers; IEEE Transaction on Medical Imaging; 29; 11; 11-2010; 1927-1941
dc.identifier.issn
0278-0062
dc.identifier.uri
http://hdl.handle.net/11336/188464
dc.description.abstract
Low noise, high resolution, fast and accurate T1 maps from MRI images of the brain can be performed using a dual flip angle method. However, Β1 field inhomogeneity, which is particularly problematic at high field strengths (e.g., 3T), limits the ability of the scanner to deliver the prescribed flip angle, introducing errors into the T1 maps that limit the accuracy of quantitative analyses based on those maps. A dual repetition time method was used for acquiring a Β1 map to correct that inhomogeneity. Additional inaccuracies due to misregistration of the acquired T1-weighted images were corrected by rigid registration, and the effects of misalignment on the T1 maps were compared to those of Β1 inhomogeneity in 19 normal subjects. However, since Β1 map acquisition takes up precious scanning time and most retrospective studies do not have Β1 map, we designed a template-based correction strategy. Β1 maps from different subjects were aligned using a twelve-parameter affine registration. Recomputed T1 maps showed an important improvement with respect to the noncorrected maps: histograms of all corrected maps exhibited two peaks corresponding to white and gray matter tissues, while unimodal histograms were observed in all uncorrected maps because of the inhomogeneity. A method to detect the best nonsubject-specific Β1 correction based on a set of features was designed. The optimum set of weighting factors for those features was computed. The best available Β1 correction was detected in almost all subjects while corrections comparable to the T 1 map corrected using the Β1 map from the same subject were detected in the others.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Institute of Electrical and Electronics Engineers
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Β1INHOMOGENEITY
dc.subject
BRAIN
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IMAGE REGISTRATION
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MAGNETIC RESONANCE IMAGES (MRI),T1 MAPPING
dc.subject.classification
Otras Ingenierías y Tecnologías
dc.subject.classification
Otras Ingenierías y Tecnologías
dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
dc.title
Template-based B1 inhomogeneity correction in 3T MRI brain studies
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-02-15T09:55:39Z
dc.identifier.eissn
1558-254X
dc.journal.volume
29
dc.journal.number
11
dc.journal.pagination
1927-1941
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Nueva Jersey
dc.description.fil
Fil: Castro, Marcelo Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Tecnologica Nacional. Facultad Regional Buenos Aires. Grupo de Investigacion y Desarrollo En Bioingenieria.; Argentina. National Institutes of Health; Estados Unidos
dc.description.fil
Fil: Yao, Jianhua. National Institutes of Health; Estados Unidos
dc.description.fil
Fil: Pang, Yuxi. National Institutes of Health; Estados Unidos. Philips Healthcare; Estados Unidos
dc.description.fil
Fil: Lee, Christabel. National Institutes of Health; Estados Unidos. University Of Georgetown; Estados Unidos
dc.description.fil
Fil: Baker, Eva. National Institutes of Health; Estados Unidos
dc.description.fil
Fil: Butman, John. National Institutes of Health; Estados Unidos
dc.description.fil
Fil: Evangelou, Iordanis E.. National Institutes of Health; Estados Unidos
dc.description.fil
Fil: Thomasson, David. National Institutes of Health; Estados Unidos
dc.journal.title
IEEE Transaction on Medical Imaging
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://ieeexplore.ieee.org/xpl/freeabs_all.jsp?arnumber=5491178
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1109/TMI.2010.2053552
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