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dc.contributor.author
Velloso, María Inés
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dc.contributor.author
Landoni, Maria Fabiana
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dc.date.available
2023-02-16T13:57:33Z
dc.date.issued
2022-03
dc.identifier.citation
Velloso, María Inés; Landoni, Maria Fabiana; Penetration enhancers for the development of intranasal formulations for use in equines; Rasayely; International Journal of Equine Science; 1; 1; 3-2022; 16-32
dc.identifier.issn
2805-3109
dc.identifier.uri
http://hdl.handle.net/11336/188262
dc.description.abstract
The aim of this review is to assess penetration enhancers, such as cyclodextrins, chitosan and their derivatives, surfactants, bileacids, their salts and derivatives, sodium taurodihidrydrofusidate, and phospholipids used in the development of intranasalformulations with a potential application in horses. In the last few years, the interest in the intranasal administration routein humans has grown because it is bloodless, noninvasive, and painless and represents a direct path toward the centralnervous system. However, in equine medicine, the use of this administration route is scarce. Since equines have a nasal cavitywith large surface area and blood irrigation, a high bioavailability of intranasal administered drugs is expected. Nowadays,the development of formulations for intranasal administration in equines is a challenge. The present review proposes theassessment of the characteristics and potential effects of the most important penetration enhancers in the development ofintranasal formulations for use in equines.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Rasayely
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
HORSES
dc.subject
CYCLODEXTRINS
dc.subject
CHITOSAN
dc.subject
SURFACTANTS
dc.subject.classification
Otras Ciencias Veterinarias
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dc.subject.classification
Ciencias Veterinarias
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dc.subject.classification
CIENCIAS AGRÍCOLAS
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dc.title
Penetration enhancers for the development of intranasal formulations for use in equines
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-02-09T15:49:39Z
dc.identifier.eissn
2805-3117
dc.journal.volume
1
dc.journal.number
1
dc.journal.pagination
16-32
dc.journal.pais
Egipto
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dc.journal.ciudad
Giza
dc.description.fil
Fil: Velloso, María Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
dc.description.fil
Fil: Landoni, Maria Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
dc.journal.title
International Journal of Equine Science
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://rasayely-journals.com/index.php/ijes/article/view/9
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