Artículo
Remembering how to run: A descriptive wheel run analysis in CF1 male and female mice
Santos, María Jimena
; Picco, Soledad
; Fernández, Rodrigo Sebastián
; Pedreira, Maria Eugenia
; Boccia, Mariano Martín
; Klappenbach, Martín
; Krawczyk, Maria del Carmen
Fecha de publicación:
06/2022
Editorial:
Elsevier
Revista:
IBRO Neuroscience Reports
ISSN:
2667-2421
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Physical exercise is known to have beneficial effects on general health and wellbeing in humans and it is also related to neuronal plasticity, increasing neurogenesis and consequently leading to improvements in processes such as learning and memory. In this sense, wheel running performance in mice appears as an extensively used behavioral approach for neurobiological studies. Here, we explored the running patterns in CF1 male and female mice allowing voluntary wheel running for 20 min along three consecutive days. We analyzed differences in the accumulated distance traveled, instant velocity, and latency to run and breaks taken in both males and females, comparing performance between days. Results revealed that after a first experience with the wheel, animals that had learnt how to run on day 1 quickly look forward to stepping into the wheel in subsequent training days, reflected by a significant increase in daily running distance and velocity. Further, no differences were found in the running performance between males and females. In summary, in a first experience with the wheel, animals get familiarized with the wheel and grow accustomed to it.
Palabras clave:
CF1-MICE
,
EXERCISE
,
LEARNING
,
MEMORY
,
SEX
,
WHEEL-RUNNING
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Licencia
Identificadores
Colecciones
Articulos(IFIBYNE)
Articulos de INST.DE FISIOL., BIOL.MOLECULAR Y NEUROCIENCIAS
Articulos de INST.DE FISIOL., BIOL.MOLECULAR Y NEUROCIENCIAS
Articulos(OCA HOUSSAY)
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Citación
Santos, María Jimena; Picco, Soledad; Fernández, Rodrigo Sebastián; Pedreira, Maria Eugenia; Boccia, Mariano Martín; et al.; Remembering how to run: A descriptive wheel run analysis in CF1 male and female mice; Elsevier; IBRO Neuroscience Reports; 12; 6-2022; 333-341
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