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dc.contributor.author
Avendaño, María Eugenia  
dc.contributor.author
Poletto, Adriana  
dc.contributor.author
Davison, Mario Ricardo  
dc.contributor.author
Bonanno, Marina Soledad  
dc.contributor.author
Zeni, Susana Noemi  
dc.date.available
2023-02-08T17:22:55Z  
dc.date.issued
2020  
dc.identifier.citation
Assessment of jawbone microarchitecture in bisphpsphonate-treated sheep by cone-beam computed tomography; LXV Reunión Anual de la Sociedad Argentina de Investigación Clínica; LXVIII Reunión Anual de la Sociedad Argentina de Inmunología; y Reunión Anual de la Sociedad Argentina Fisiología; Mar del Plata; Argentina; 2020; 1-6  
dc.identifier.issn
0025-7680  
dc.identifier.uri
http://hdl.handle.net/11336/187348  
dc.description.abstract
The cone-beam computed tomography (CBCT) is a non-invasive 3D reconstruction technique that enables to assess jawbone micro-architecture. It is used to illustrate results through 3D images. In the present report, the combination of CBCT with other techniques was used to evaluate changes in composition and micro-architectural structure quantity of the ewe jawbone after oestrogen withdrawal (OVX) and/or chronic treatment with high doses of zoledronic acid (zol). Three groups of adult Corriedale ewes, 35 to 40 kg body weight were used: OVX: OVX ewes receiving saline solution; ZOL: OVX ewes treated with Zol (4 mg/month) for 28 months for high cumulative dose of ZOL in bones and SHAM: SHAM ewes receiving saline solution (control). At the end of the study, hemi-mandibles were extracted: Bone mineral density (BMD) and content (BMC) of the mandibles were evaluated ex vivo by DXA (Lunar DPX); CBCT was performed using Planmeca Promax 3D Classic. Results of CBCT: OVX as compared to SHAM ewes significantly decreased BMC and BMD (p<0.001); BV/ TV (%), Tb. Th, connectivity and anisotropy (p<0.0075; p<0.0075, p<0.001 and p<0.02, respectively) while Tb. Sp (p<0.0002) was significantly increased. Zol treatment did not show statistical differences when compared to SHAM group. Zol showed values of anisotropy significantly higher than OVX group (p<0.018) and Tb.Sp significantly lower than OVX groups (p<0.043). BV/ TV (%), Tb. Th and connectivity as compared to OVX group showed a clear tendency to be higher and almost reached significance (p=0.055; p=0.061 and p=0.054, respectively. Maxillary BMC and BMD were lowest in OVX ewes (p<0.05) and were significantly higher in ZOL than in SHAM ewes (p<0.05). Conclusion: The CBCT technique was useful to evaluate the deterioration of the bone quality by estrogen withdrawal and the recovery by ZOL treatment.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Fundación Revista Medicina  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
JAW BONE  
dc.subject
CBCT TECHNIQUE  
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ESTROGEN  
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BISPHOSPHONATES  
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Otras Ciencias Médicas  
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Otras Ciencias Médicas  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Assessment of jawbone microarchitecture in bisphpsphonate-treated sheep by cone-beam computed tomography  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.type
info:eu-repo/semantics/conferenceObject  
dc.type
info:ar-repo/semantics/documento de conferencia  
dc.date.updated
2022-11-01T22:47:26Z  
dc.journal.volume
80  
dc.journal.number
5  
dc.journal.pagination
1-6  
dc.journal.pais
Argentina  
dc.journal.ciudad
Ciudad de Buenos Aires  
dc.description.fil
Fil: Avendaño, María Eugenia. Universidad Nacional de Cuyo. Facultad de Odontologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Poletto, Adriana. Universidad Nacional de Cuyo. Facultad de Odontologia; Argentina  
dc.description.fil
Fil: Davison, Mario Ricardo. Universidad Nacional de Rio Negro. Sede Alto Valle y Valle Medio.; Argentina  
dc.description.fil
Fil: Bonanno, Marina Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina  
dc.description.fil
Fil: Zeni, Susana Noemi. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://medicinabuenosaires.com/revistas/vol80-20/s5/Mv80s5.pdf  
dc.conicet.rol
Autor  
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Autor  
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Autor  
dc.conicet.rol
Autor  
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Autor  
dc.coverage
Internacional  
dc.type.subtype
Reunión  
dc.description.nombreEvento
LXV Reunión Anual de la Sociedad Argentina de Investigación Clínica; LXVIII Reunión Anual de la Sociedad Argentina de Inmunología; y Reunión Anual de la Sociedad Argentina Fisiología  
dc.date.evento
2020-11-10  
dc.description.ciudadEvento
Mar del Plata  
dc.description.paisEvento
Argentina  
dc.type.publicacion
Journal  
dc.description.institucionOrganizadora
Sociedad Argentina de Investigación Clínica  
dc.description.institucionOrganizadora
Sociedad Argentina de Inmunología  
dc.description.institucionOrganizadora
Sociedad Argentina De Fisiología  
dc.source.revista
Medicina (Buenos Aires)  
dc.date.eventoHasta
2020-11-13  
dc.type
Reunión