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dc.contributor.author
Tejada Jacob, Guillermo Ivan  
dc.contributor.author
Castro, Guillermo Raul  
dc.contributor.author
Alvarez, Vera Alejandra  
dc.contributor.other
Shadpour Mallakpour  
dc.contributor.other
Chaudhery Mustansar Hussain  
dc.date.available
2023-02-06T03:40:26Z  
dc.date.issued
2021  
dc.identifier.citation
Tejada Jacob, Guillermo Ivan; Castro, Guillermo Raul; Alvarez, Vera Alejandra; Nanotechnology applied to personalized 3D dressings for diabetic feet; Springer Nature Switzerland AG; 2021; 1-24  
dc.identifier.isbn
978-981-15-6453-6  
dc.identifier.uri
http://hdl.handle.net/11336/186913  
dc.description.abstract
Advances in nanotechnology are showing a major impact in the manufacture of biomaterials, electronics, and medicine. Nanotechnology based on biopolymers is a new strategy for the diagnosis and treatment of local diseases and infections. There is a wide range of applications for nanotechnology in the field of drug administration because this technology has improved the delivery of drugs to areas that were unfavorable to macromolecules, where it is targeted to specific sites and goal oriented. There is a wide range of nanoparticulate systems like carbon nanotubes, metallic nanoparticles, polymeric nanoparticles, and lipid nanoparticles, among others. The development of nanoparticles loaded with antibacterial drugs for the treatment of infections could improve the pharmacological therapy of the patient. These nanosystems should be placed on a vehicle for the design of enhanced dressings.Another technology that has become very relevant in the present day is 3D bioprinting, and relevant in the field of dressings, advances have been done. 3D bioprinting is largely performed with one of three additive manufacturing techniques: inkjet printing, extrusion printing, and laser-assisted printing. All three techniques require cells, biomolecules, and proteins to be suspended within a biotint that can be 3D printed. The developed hydrogels based on natural, nontoxic, biodegradable, and non-immunogenic linear polysaccharides with the addition of antibiotics and molecules with biological activity are the challenge of both 3D bioprinting and nanotechnology for the treatment of severe diseases or infections and thus improve the pharmacological therapy of the patient.Diabetic foot is an infection, ulceration, and destruction of deep tissues, associated with loss of sensitivity to pain and peripheral vascular disease of varying severity in the lower extremities. Foot ulcers in people with diabetes are one of the main causes for possible amputation. In the presence of necrotic tissue, as in the case of diabetic foot, treatment by debridement, removal of necrotic tissue and bacterial load from the wound bed, is recommended to decrease infection, pain, odor, and wound complications acute or chronic.This article proposes the development of nanosystems loaded with antimicrobial drug incorporated in personalized dressings in the 3D bioprinter for diabetic feet.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer Nature Switzerland AG  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
3D bioprinter  
dc.subject
Diabetic fee  
dc.subject
Nanoparticles  
dc.subject
Dressing  
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Otras Biotecnologías de la Salud  
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Biotecnología de la Salud  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Nanotechnology applied to personalized 3D dressings for diabetic feet  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.type
info:eu-repo/semantics/bookPart  
dc.type
info:ar-repo/semantics/parte de libro  
dc.date.updated
2022-09-20T17:59:45Z  
dc.journal.pagination
1-24  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
New York  
dc.description.fil
Fil: Tejada Jacob, Guillermo Ivan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina  
dc.description.fil
Fil: Castro, Guillermo Raul. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Fermentaciones Industriales. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Fermentaciones Industriales; Argentina  
dc.description.fil
Fil: Alvarez, Vera Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/referenceworkentry/10.1007/978-981-15-6453-6_45-1  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/978-981-15-6453-6_45-1  
dc.conicet.paginas
520  
dc.source.titulo
Handbook of Consumer Nanoproducts