Artículo
Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions
Rodriguez Granillo, Gaston Alfredo
; Rosales, Miguel A.; Renes, Paola; Diez, Eduardo; Pereyra, Jorge; Gomez, Estela; De Lillo, Gustavo; Degrossi, Elina; Rodriguez, Alfredo E.; McFadden, Eugene P.
Fecha de publicación:
03/2010
Editorial:
Elsevier
Revista:
Journal of Cardiovascular Computed Tomography
ISSN:
1934-5925
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Background: Hypoenhanced regions on multidetector CT (MDCT) coronary angiography correlate with myocardial hyperperfusion. In addition to a limited capillary density, chronic myocardial infarction (MI) commonly contains a considerable amount of adipose tissue. Objective: We explored whether regional myocardial hypoenhancement on contrast-enhanced MDCT could be identified with standard coronary artery calcium (CAC) scoring acquisitions with noncontrast CT. Methods: Consecutive patients with a history of MI who were referred for contrast-enhanced MDCT from November 2006 until March 2009 were studied. Noncontrast CT for CAC scoring was also performed. The correlation between regional myocardial hypoenhancement on contrast-enhanced CT and regional myocardial hypoattenuated areas on noncontrast CT was defined. Results: Eighty-three patients (mean age, 61.5 ± 12.5 years; n = 67; 81% male) with previous MI were studied. A total of 1411 myocardial segments were evaluated. Two hundred thirty-nine segments (17%) showed myocardial hypoenhancement by MDCT and 140 segments (9.6%) by CAC. On a patient level, noncontrast CT showed a sensitivity, specificity, positive predictive value, (PPV) and negative predictive value (NPV) of 66% (95% CI, 0.53-0.77), 100% (95% CI, 0.76-1.00), 100% (95% CI, 0.90-1.00), and 41% (95% CI, 0.26-0.58), respectively, to detect myocardial hypoenhancement. On a per segment level, noncontrast CT showed a sensitivity, specificity, PPV, and NPV of 58% (95% CI, 0.51-0.64), 100% (95% CI, 0.99-1.00), 99% (95% CI, 0.94-1.00), and 92% (95% CI, 0.90-0.93), respectively, to detect myocardial hypoenhancement. Conclusions: Our findings suggest that chronic MI can be detected with standard CAC scoring acquisitions. © 2010 Society of Cardiovascular Computed Tomography.
Palabras clave:
COMPUTED TOMOGRAPHY
,
INFARCT EXTENSION
,
NECROSIS
,
PERFUSION DEFECT
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Articulos de SEDE CENTRAL
Citación
Rodriguez Granillo, Gaston Alfredo; Rosales, Miguel A.; Renes, Paola; Diez, Eduardo; Pereyra, Jorge; et al.; Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions; Elsevier; Journal of Cardiovascular Computed Tomography; 4; 2; 3-2010; 99-107
Compartir
Altmétricas