Mostrar el registro sencillo del ítem

dc.contributor.author
Guastavino, Javier Fernando  
dc.contributor.author
Vaillard, Victoria Anahi  
dc.contributor.author
Cristaldi, Mariano Daniel  
dc.contributor.author
Rossini, Lorena Noemí  
dc.contributor.author
Vaillard, Santiago Eduardo  
dc.date.available
2017-06-22T15:43:20Z  
dc.date.issued
2016-06  
dc.identifier.citation
Guastavino, Javier Fernando; Vaillard, Victoria Anahi; Cristaldi, Mariano Daniel; Rossini, Lorena Noemí; Vaillard, Santiago Eduardo; Simple Synthesis of Aldehyde and Carboxylic Acid Terminated Methoxypoly (ethylene glycol); Wiley Vch Verlag; Macromolecular Chemistry And Physics; 217; 15; 6-2016; 1745-1751  
dc.identifier.issn
1022-1352  
dc.identifier.uri
http://hdl.handle.net/11336/18636  
dc.description.abstract
mPEG-aldehydes and activated mPEG-carboxylic acids on which the polymer and the reactive functional group are separated by aliphatic chains of different lengths, are well known reagents of widespread application in PEGylation technology. The syntheses of these functional polymers are not easy and usually the preparation of each of these compounds requires a very specific set of reagents and experimental conditions. In fact, a general method for their preparation is, still nowadays, unavailable. In this work a simple synthetic method is developed for preparation of mPEG-aldehydes and carboxylic acids with excellent yields. The key step of themethod involves a substitution reaction of mPEG-mesylate with mono-alkoxides of symmetricaldiols to afford hydroxyl-terminated polymers, which are convertedto the aldehydes and acids by mild oxidation reactions.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Wiley Vch Verlag  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Pegylation  
dc.subject
Peg Derivative  
dc.subject
Peg Aldehyde  
dc.subject
Peg Acid  
dc.subject.classification
Físico-Química, Ciencia de los Polímeros, Electroquímica  
dc.subject.classification
Ciencias Químicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Simple Synthesis of Aldehyde and Carboxylic Acid Terminated Methoxypoly (ethylene glycol)  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2017-06-21T18:41:05Z  
dc.journal.volume
217  
dc.journal.number
15  
dc.journal.pagination
1745-1751  
dc.journal.pais
Alemania  
dc.journal.ciudad
Weinheim  
dc.description.fil
Fil: Guastavino, Javier Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico Para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico Para la Industria Química; Argentina  
dc.description.fil
Fil: Vaillard, Victoria Anahi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico Para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico Para la Industria Química; Argentina  
dc.description.fil
Fil: Cristaldi, Mariano Daniel. Carbonfe; Argentina  
dc.description.fil
Fil: Rossini, Lorena Noemí. Carbonfe; Argentina  
dc.description.fil
Fil: Vaillard, Santiago Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico Para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico Para la Industria Química; Argentina  
dc.journal.title
Macromolecular Chemistry And Physics  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/macp.201600094/abstract  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/macp.201600094