Distinct Mechanisms of Dissemination of NDM-1 Metallo-β-Lactamase in Acinetobacter Species in Argentina

A 4-year surveillance of carbapenem-resistant Acinetobacter spp. isolates in Argentina identified 40 strains carrying blaNDM-1. Genome sequencing revealed that most were Acinetobacter baumannii, whereas seven represented other Acinetobacter spp. The A. baumannii genomes were closely related, suggesting recent spread. blaNDM-1 was located in the chromosome of A. baumannii strains and on a plasmid in non-A. baumannii strains. A resistance gene island carrying blaPER-7 and other resistance determinants was found on a plasmid in some A. baumannii strains.

Palabras clave: ACINETOBACTER , ACINETOBACTER BAUMANNII , CARBAPENEM RESISTANCE , CARBAPENEMS , NDM-1

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Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)

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URI: http://hdl.handle.net/11336/184743

URL: https://aac.asm.org/content/64/5/e00324-20

DOI: http://dx.doi.org/10.1128/AAC.00324-20

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Articulos(IBR)
Articulos de INST.DE BIOLOGIA MOLECULAR Y CELULAR DE ROSARIO

Citación

Adams, Mark D.; Pasteran, Fernando; Traglia, German Matias; Martinez, Jasmine; Huang, Fanny; et al.; Distinct Mechanisms of Dissemination of NDM-1 Metallo-β-Lactamase in Acinetobacter Species in Argentina; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 64; 5; 4-2020; 1-13

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