Mostrar el registro sencillo del ítem
dc.contributor.author
Moreno Ruiz, Beatriz
dc.contributor.author
Mellado, Susana
dc.contributor.author
Zamora Moratalla, Alfonsa
dc.contributor.author
Albarracin, Ana Lia
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.contributor.author
Martín, Eduardo D.
dc.date.available
2023-01-10T12:27:27Z
dc.date.issued
2021-02
dc.identifier.citation
Moreno Ruiz, Beatriz; Mellado, Susana; Zamora Moratalla, Alfonsa; Albarracin, Ana Lia; Martín, Eduardo D.; Increase in serum prolactin levels in females improves the performance of spatial learning by promoting changes in the circuital dynamics of the hippocampus; Pergamon-Elsevier Science Ltd; Psychoneuroendocrinology; 124; 2-2021; 1-8
dc.identifier.issn
0306-4530
dc.identifier.uri
http://hdl.handle.net/11336/184088
dc.description.abstract
Beyond the direct physiological functions associated with motherhood in mammals, previous studies have suggested the potential role of prolactin (Prl) in distinct brain processes such as neuroprotection, neurogenesis, and stress responses. However, the cognitive influence of Prl remains unclear, particularly regarding the mechanisms of acquisition, consolidation and retrieval of information in the brain. Using chronic implanted electrodes in freely moving female mice combined with behavioral tests, we investigated the rhythmic activity changes induced by Prl in a model of hippocampus-dependent learning and memory. Our results show that Prl improves the learning of a spatial memory task in the acquisition stage. The main variations at the circuitry level were in the theta frequency band (4−8 Hz and 8−12 Hz), marked by a faster change in oscillatory activity with no modifications to higher frequencies. These results show that Prl plays a significant role in the acquisition of information during learning of a spatial memory task, suggesting that an increase in Prl levels may induce changes in circuital network plasticity.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Pergamon-Elsevier Science Ltd
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
CIRCUITAL NETWORK PLASTICITY
dc.subject
HYPERPROLACTINEMIA
dc.subject
LACTANCY
dc.subject
RHYTHMIC ACTIVITY
dc.subject.classification
Neurociencias
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
Medicina Básica
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.title
Increase in serum prolactin levels in females improves the performance of spatial learning by promoting changes in the circuital dynamics of the hippocampus
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-09-07T14:44:17Z
dc.journal.volume
124
dc.journal.pagination
1-8
dc.journal.pais
Estados Unidos
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.description.fil
Fil: Moreno Ruiz, Beatriz. INSTITUTO CAJAL ; CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;
dc.description.fil
Fil: Mellado, Susana. INSTITUTO CAJAL ; CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;
dc.description.fil
Fil: Zamora Moratalla, Alfonsa. INSTITUTO CAJAL ; CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;
dc.description.fil
Fil: Albarracin, Ana Lia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina
dc.description.fil
Fil: Martín, Eduardo D.. INSTITUTO CAJAL ; CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;
dc.journal.title
Psychoneuroendocrinology
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0306453020304716
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.psyneuen.2020.105048
Archivos asociados