Mostrar el registro sencillo del ítem

dc.contributor.author
Aguirre, Matías Ezequiel  
dc.contributor.author
Marino, Ignacio  
dc.contributor.author
Bozzano, Patricia Beatriz  
dc.contributor.author
Feldhoff, Armin  
dc.contributor.author
Grela, Maria Alejandra  
dc.date.available
2023-01-02T18:37:11Z  
dc.date.issued
2019-07  
dc.identifier.citation
Aguirre, Matías Ezequiel; Marino, Ignacio; Bozzano, Patricia Beatriz; Feldhoff, Armin; Grela, Maria Alejandra; Magnetic ZIF-8 as a stable support for biomolecules via adsorption in aqueous buffered solutions at pH = 7; Elsevier Science; Inorganic Chemistry Communications; 105; 7-2019; 225-229  
dc.identifier.issn
1387-7003  
dc.identifier.uri
http://hdl.handle.net/11336/182961  
dc.description.abstract
Metal-organic frameworks (MOFs) have been recently proposed as supports for biomolecules immobilization, particularly for enzymes. However, their stability under the high ionic strength aqueous solutions required for practical applications of these biocatalysts have not been evaluated. Here, it is shown that surface modifications and a careful analysis and selection of the buffer components must be accomplished to ensure the resistance of the MOF to hydrolysis, even for the previously assumed robust Zeolitic Imidazole Frameworks (ZIFs). By taking into account these considerations, and introducing polyvinylpyrrolidone (PVP) as a surfactant in the synthetic process, a resistant and stable magnetic MOF (Fe 3 O 4 @ZIF-8/PVP) was obtained. Further, the loading capacity of the stabilized synthetized structures for the immobilization of a model protein, such as bovine serum albumin (BSA), was analyzed. It was found that physical interaction provides an efficient and suitable method to immobilize this biomolecule without evidence of leaching.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier Science  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
ADSORPTION  
dc.subject
BIOMOLECULE SUPPORT  
dc.subject
BUFFERED MEDIA  
dc.subject
METAL-ORGANIC FRAMEWORKS  
dc.subject
ZIF-8 STABILITY  
dc.subject.classification
Otras Ciencias Químicas  
dc.subject.classification
Ciencias Químicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Magnetic ZIF-8 as a stable support for biomolecules via adsorption in aqueous buffered solutions at pH = 7  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2022-11-17T17:36:36Z  
dc.journal.volume
105  
dc.journal.pagination
225-229  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Amsterdam  
dc.description.fil
Fil: Aguirre, Matías Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Físicas de Mar del Plata. Grupo de Investigación del Departamento de Química de la Unmdp | Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Físicas de Mar del Plata. Grupo de Investigación del Departamento de Química de la Unmdp; Argentina  
dc.description.fil
Fil: Marino, Ignacio. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Departamento de Química; Argentina  
dc.description.fil
Fil: Bozzano, Patricia Beatriz. Comisión Nacional de Energía Atómica. Centro Atómico Constituyentes; Argentina. Universidad Nacional de San Martín. Instituto Sabato; Argentina  
dc.description.fil
Fil: Feldhoff, Armin. Leibniz Universitat Hannover; Alemania  
dc.description.fil
Fil: Grela, Maria Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Físicas de Mar del Plata. Grupo de Investigación del Departamento de Química de la Unmdp | Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Físicas de Mar del Plata. Grupo de Investigación del Departamento de Química de la Unmdp; Argentina  
dc.journal.title
Inorganic Chemistry Communications  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S1387700319300954  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.inoche.2019.05.013