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dc.contributor.author
Vila, Jorge Alberto
dc.date.available
2022-12-28T18:15:04Z
dc.date.issued
2021-07
dc.identifier.citation
Vila, Jorge Alberto; Thoughts on the protein's native state; American Chemical Society; Journal of Physical Chemistry Letters; 12; 25; 7-2021; 5963-5966
dc.identifier.issn
1948-7185
dc.identifier.uri
http://hdl.handle.net/11336/182750
dc.description.abstract
The presence of metamorphism in the protein's native state is not yet fully understood. To shed light on this issue, we present an assessment, in terms of the amide hydrogen exchange protection factor, that aims to determine the possible existence of structural fluctuations in the native-state consistent with both the upper-bound marginal stability of proteins and the presence of metamorphism. The preliminary results enable us to conclude that the native-state metamorphism is, indeed, more probable than previously thought.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
American Chemical Society
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Metamorphism
dc.subject
Native State
dc.subject
Anfinsen
dc.subject
Gershgorin
dc.subject.classification
Física Atómica, Molecular y Química
dc.subject.classification
Ciencias Físicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Thoughts on the protein's native state
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-10-04T14:39:59Z
dc.identifier.eissn
1948-7185
dc.journal.volume
12
dc.journal.number
25
dc.journal.pagination
5963-5966
dc.journal.pais
Estados Unidos
dc.description.fil
Fil: Vila, Jorge Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Matemática Aplicada de San Luis "Prof. Ezio Marchi". Universidad Nacional de San Luis. Facultad de Ciencias Físico, Matemáticas y Naturales. Instituto de Matemática Aplicada de San Luis "Prof. Ezio Marchi"; Argentina
dc.journal.title
Journal of Physical Chemistry Letters
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/acs.jpclett.1c01831
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1021/acs.jpclett.1c01831
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