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dc.contributor.author
Rodriguez Granillo, Gaston Alfredo
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dc.contributor.author
Carrascosa, Patricia
dc.contributor.author
Goldsmit, Alejandro
dc.contributor.author
Arbab Zadeh, Armin
dc.date.available
2022-12-28T14:56:33Z
dc.date.issued
2019-11
dc.identifier.citation
Rodriguez Granillo, Gaston Alfredo; Carrascosa, Patricia; Goldsmit, Alejandro; Arbab Zadeh, Armin; Invasive coronary angiography findings across the CAD-RADS classification spectrum; Springer; International Journal Of Cardiovascular Imaging; 35; 11; 11-2019; 1955-1961
dc.identifier.issn
1569-5794
dc.identifier.uri
http://hdl.handle.net/11336/182722
dc.description.abstract
The recently introduced coronary artery disease reporting and data system (CAD-RADS) evaluated by computed tomography and based on stenosis severity, might not adequately reflect the complexity of CAD. We explored the relationship between CAD-RADS and the spatial distribution, burden, and complexity of lesions by invasive coronary angiography (ICA). Stable patients who underwent coronary computed tomography angiography (CCTA) and ICA comprised the study population. Patients were classified according to the CAD-RADS: 0, No plaque; 1, 1–24% stenosis; 2, 25–49%; 3, 50–69%; 4A, 70–99%; 4B, left main stenosis or 3-vessel obstructive disease; and 5, total occlusion. Based on ICA findings, we calculated the SYNTAX score and the CAD extension index. Ninety-one patients were included, with a mean age of 61.4 ± 10.5 years (74% male). We found significant relationships between CAD-RADS and both the SYNTAX score (p < 0.0001) and the CAD extension index (p < 0.0001), although the complexity of coronary anatomy differed among patients with CAD-RADS ≥ 4A. Among patients with CAD-RADS < 4, the mean segment involvement score (SIS) was 8.4 ± 4.0, 52% of them with a SIS > 5. Of the 30 patients with CAD-RADS 5, 9 (30%) affected distal segments or secondary branches, and 9 (30%) had concomitant severe non-extensive disease at ICA. Regarding the spatial distribution of the non-occluded most severe lesions, 27 (44%) comprised distal segments or secondary branches. In the present study including a high-risk population, we identified diverse coronary anatomy complexity scenarios and relevant differences in spatial distribution sharing the same CAD-RADS classification.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Springer
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dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
COMPUTED TOMOGRAPHY
dc.subject
CORONARY ARTERY STENOSIS
dc.subject
PLAQUE BURDEN
dc.subject
SYNTAX SCORE
dc.subject.classification
Sistemas Cardíaco y Cardiovascular
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dc.subject.classification
Medicina Clínica
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Invasive coronary angiography findings across the CAD-RADS classification spectrum
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-12-28T14:01:27Z
dc.identifier.eissn
1573-0743
dc.journal.volume
35
dc.journal.number
11
dc.journal.pagination
1955-1961
dc.journal.pais
Alemania
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dc.journal.ciudad
Berlin
dc.description.fil
Fil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina. Diagnóstico Maipú; Argentina
dc.description.fil
Fil: Carrascosa, Patricia. Diagnóstico Maipú; Argentina
dc.description.fil
Fil: Goldsmit, Alejandro. Sanatorio Guemes Sociedad Anonima.; Argentina
dc.description.fil
Fil: Arbab Zadeh, Armin. University Johns Hopkins; Estados Unidos
dc.journal.title
International Journal Of Cardiovascular Imaging
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://link.springer.com/10.1007/s10554-019-01654-1
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s10554-019-01654-1
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