Artículo

Iota-Carrageenan Prevents the Replication of SARS-CoV-2 in a Human Respiratory Epithelium Cell Line in vitro

Varese, AugustoIcon ; Paletta, Ana LuzIcon ; Ceballos, AnaIcon ; Palacios, Carlos AdolfoIcon ; Figueroa, Juan Manuel; Dugour, Andrea Vanesa
Fecha de publicación: 12/2021
Editorial: Frontiers Media
Revista: Frontiers in Virology
e-ISSN: 2673-818X
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Iota-carrageenan is a sulfated polysaccharide extracted from red seaweeds, which, formulated into a nasal spray, has already been proven safe and effective in viral upper respiratory infections. In Calu-3, a human respiratory epithelium cell line, we explored the activity of a formula of iota-carrageenan and sodium chloride against SARS-CoV-2. In this study, the assayed formula, already approved as a nasal spray for human use, effectively inhibited SARS-CoV-2 infection, providing a more substantial reference for clinical studies or developments.
Palabras clave: CARRAGEENANS , SARS-COV-2 , NASAL SPRAY , COVID-19
 
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Licencia
info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution 2.5 Unported (CC BY 2.5)
Identificadores
URI: http://hdl.handle.net/11336/182459
URL: https://www.frontiersin.org/articles/10.3389/fviro.2021.746824/full
DOI: http://dx.doi.org/10.3389/fviro.2021.746824
Colecciones
Articulos(ICT - MILSTEIN)
Articulos de INST.DE CS. Y TECNOLOGIA "DR. CESAR MILSTEIN"
Articulos(INBIRS)
Articulos de INSTITUTO DE INVESTIGACIONES BIOMEDICAS EN RETROVIRUS Y SIDA
Citación
Varese, Augusto; Paletta, Ana Luz; Ceballos, Ana; Palacios, Carlos Adolfo; Figueroa, Juan Manuel; et al.; Iota-Carrageenan Prevents the Replication of SARS-CoV-2 in a Human Respiratory Epithelium Cell Line in vitro; Frontiers Media; Frontiers in Virology; 1; 746824; 12-2021; 1-7
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