Artículo
Decoding brain states on the intrinsic manifold of human brain dynamics across wakefulness and sleep
Rué Queralt, Joan; Stevner, Angus; Tagliazucchi, Enzo Rodolfo
; Laufs, Helmut; Kringelbach, Morten L.; Deco, Gustavo; Atasoy, Selen
![Icon](/themes/CONICETDigital/images/conicet.png)
Fecha de publicación:
12/2021
Editorial:
Nature Publishing Group
Revista:
Communications Biology
e-ISSN:
2399-3642
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Current state-of-the-art functional magnetic resonance imaging (fMRI) offers remarkable imaging quality and resolution, yet, the intrinsic dimensionality of brain dynamics in different states (wakefulness, light and deep sleep) remains unknown. Here we present a method to reveal the low dimensional intrinsic manifold underlying human brain dynamics, which is invariant of the high dimensional spatio-temporal representation of the neuroimaging technology. By applying this intrinsic manifold framework to fMRI data acquired in wakefulness and sleep, we reveal the nonlinear differences between wakefulness and three different sleep stages, and successfully decode these different brain states with a mean accuracy across participants of 96%. Remarkably, a further group analysis shows that the intrinsic manifolds of all participants share a common topology. Overall, our results reveal the intrinsic manifold underlying the spatiotemporal dynamics of brain activity and demonstrate how this manifold enables the decoding of different brain states such as wakefulness and various sleep stages.
Palabras clave:
NEUROSCIENCE
,
CONSCIOUSNESS
,
FMRI
,
MACHINE LEARNING
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Colecciones
Articulos(IFIBA)
Articulos de INST.DE FISICA DE BUENOS AIRES
Articulos de INST.DE FISICA DE BUENOS AIRES
Citación
Rué Queralt, Joan; Stevner, Angus; Tagliazucchi, Enzo Rodolfo; Laufs, Helmut; Kringelbach, Morten L.; et al.; Decoding brain states on the intrinsic manifold of human brain dynamics across wakefulness and sleep; Nature Publishing Group; Communications Biology; 4; 1; 12-2021; 1-11
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