Artículo
In vitro Interference of a Glyphosate Commercial Formulation with the Stimulation of Ovarian Maturation by Progesterone, in the Estuarine Crab Neohelice granulata
Canosa, Ivana Sofía
; Silveyra, Gabriela Romina
; Lonné, María Noelia
; Medesani, Daniel Alberto
; Rodriguez, Enrique Marcelo
Fecha de publicación:
01/2021
Editorial:
Springer
Revista:
Bulletin of Environmental Contamination and Toxicology
ISSN:
0007-4861
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
This study was aimed at evaluating the possible interference of formulated glyphosate to the endocrine control of ovarian growth exerted by progesterone, in the estuarine crab Neohelice granulata. The addition of Roundup Ultramax® (0.2 mg/L of glyphosate in the incubation medium) was able to potentiate the stimulating effect of progesterone on total vitellogenic protein (Vg) content of ovarian pieces from crabs. Moreover, the sole addition of mifepristone (antagonist of progesterone receptors) was able to produce a decrement of the Vg content, which was not reverted by the addition of Roundup. A similar result was confirmed by means of histological analysis, which showed that mifepristone, both alone and in combination with Roundup, inhibited ovarian maturation, while Roundup alone increased it, in terms of a higher proportion of vitellogenic oocytes. We conclude that Roundup could stimulate the progesterone secretion exerted by the ovary and/or could act as a partial agonist of this hormone in the same tissue.
Palabras clave:
ESTUARINE CRABS
,
GLYPHOSATE
,
OVARIAN GROWTH
,
PROGESTERONE
,
VITELLOGENIC PROTEINS
Archivos asociados
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Identificadores
Colecciones
Articulos (IIIA)
Articulos de INSTITUTO DE INVESTIGACION E INGENIERIA AMBIENTAL
Articulos de INSTITUTO DE INVESTIGACION E INGENIERIA AMBIENTAL
Articulos(IBBEA)
Articulos de INSTITUTO DE BIODIVERSIDAD Y BIOLOGIA EXPERIMENTAL Y APLICADA
Articulos de INSTITUTO DE BIODIVERSIDAD Y BIOLOGIA EXPERIMENTAL Y APLICADA
Citación
Canosa, Ivana Sofía; Silveyra, Gabriela Romina; Lonné, María Noelia; Medesani, Daniel Alberto; Rodriguez, Enrique Marcelo; In vitro Interference of a Glyphosate Commercial Formulation with the Stimulation of Ovarian Maturation by Progesterone, in the Estuarine Crab Neohelice granulata; Springer; Bulletin of Environmental Contamination and Toxicology; 106; 4; 1-2021; 583-588
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