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dc.contributor.author
Kvarik, Timea
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dc.contributor.author
Mammel, Barbara
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dc.contributor.author
Reglodi, Dora
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dc.contributor.author
Antonelli, Marta Cristina
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dc.contributor.author
Farkas, Jozsef
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dc.contributor.author
Tamas, Andrea
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dc.contributor.author
Ertl, Tibor
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dc.contributor.author
Atlasz, Tamas
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dc.contributor.author
Bodzai, Greta
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Kiss, Peter
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dc.contributor.author
Gyarmati, Judit
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dc.date.available
2017-06-08T20:19:54Z
dc.date.issued
2016-02
dc.identifier.citation
Kvarik, Timea; Mammel, Barbara; Reglodi, Dora; Antonelli, Marta Cristina; Farkas, Jozsef; et al.; Effects of maternal stress during different periods of pregnancy on the early neurobehavioral response of rats; Insight Medical Publishing; Journal of Neurology and Neuroscience; 7; 2; 2-2016; 1-8
dc.identifier.issn
2171-6625
dc.identifier.uri
http://hdl.handle.net/11336/17824
dc.description.abstract
Background: Several studies focus on the effects of prenatal stress in adulthood. Relatively little is known about the early neurodevelopmental consequences of such experiences and their predictive value. Thus we examined the early neurobehavioral responses of offspring whose mothers were exposed to restraint stress. Methods and results: Pregnant rats were exposed to 60 minutes restraint stress twice a day for seven days in different periods of pregnancy (early/mid and late phase). After birth, offspring were examined for the maturation of neural signs and reflexes daily for 3 weeks. Mid-pregnancy stress resulted in a subtle faster development in the appearance of eyelid and auditory startle reflexes, and in the disappearance of crossed extensor reflex. Pups exposed to stress in the last week of intrauterine life displayed a delay in air righting and showed a slight enhancement in the appearance of auditory startle. Conclusion: Based on our present findings, the deleterious consequences of prenatal stress are not apparent during the early developmental stages at least not detectable with the battery of test most widely used to examine neurobehavioral development. However, these findings draw the attention of the need of careful awareness in later ages in spite of the normal neurobehavioral development of newborns exposed to prenatal stress.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Insight Medical Publishing
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
Restraint Stress Prenatal
dc.subject
Maternal
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Nerobehavioral
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Development
dc.subject
Rat
dc.subject.classification
Neurociencias
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dc.subject.classification
Medicina Básica
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Effects of maternal stress during different periods of pregnancy on the early neurobehavioral response of rats
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-06-07T20:38:47Z
dc.journal.volume
7
dc.journal.number
2
dc.journal.pagination
1-8
dc.journal.pais
Estados Unidos
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dc.journal.ciudad
Wilmington
dc.description.fil
Fil: Kvarik, Timea. University of Pécs; Hungría
dc.description.fil
Fil: Mammel, Barbara. University of Pécs; Hungría
dc.description.fil
Fil: Reglodi, Dora. University of Pécs; Hungría
dc.description.fil
Fil: Antonelli, Marta Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencia "Prof. Eduardo de Robertis". Universidad de Buenos Aires. Facultad de Medicina. Instituto de Biología Celular y Neurociencia; Argentina
dc.description.fil
Fil: Farkas, Jozsef. University of Pécs; Hungría
dc.description.fil
Fil: Tamas, Andrea. University of Pécs; Hungría
dc.description.fil
Fil: Ertl, Tibor. University of Pécs; Hungría
dc.description.fil
Fil: Atlasz, Tamas. University of Pécs; Hungría
dc.description.fil
Fil: Bodzai, Greta. University of Pécs; Hungría
dc.description.fil
Fil: Kiss, Peter. University of Pécs; Hungría
dc.description.fil
Fil: Gyarmati, Judit. University of Pécs; Hungría
dc.journal.title
Journal of Neurology and Neuroscience
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.jneuro.com/neurology-neuroscience/effects-of-maternal-stress-during-different-periods-of-pregnancy-on-the-early-neurobehavioral-response-of-rats.php?aid=8703
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.21767/2171-6625.100080
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