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dc.contributor.author
González, Ana Silvia
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dc.contributor.author
Affranchino, Jose Luis
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dc.date.available
2022-11-04T12:31:59Z
dc.date.issued
2018-05
dc.identifier.citation
González, Ana Silvia; Affranchino, Jose Luis; Properties and Functions of Feline Immunodeficiency Virus Gag Domains in Virion Assembly and Budding; MDPI AG; Viruses; 10; 5; 5-2018; 1-16
dc.identifier.issn
1999-4915
dc.identifier.uri
http://hdl.handle.net/11336/176381
dc.description.abstract
Feline immunodeficiency virus (FIV) is an important cat pathogen worldwide whose biological and pathophysiological properties resemble those of human immunodeficiency virus type 1 (HIV-1). Therefore, the study of FIV not only benefits its natural host but is also useful for the development of antiviral strategies directed against HIV-1 infections in humans. FIV assembly results from the multimerization of a single but complex viral polypeptide, the Gag precursor. In this review, we will first give an overview of the current knowledge of the proteins encoded by the FIV pol, env, rev, vif, and orf-A genes, and then we will describe and discuss in detail the critical roles that each of the FIV Gag domains plays in virion morphogenesis. Since retroviral assembly is an attractive target for therapeutic interventions, gaining a better understanding of this process is highly desirable.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
MDPI AG
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
FELINE IMMUNODEFICIENCY VIRUS
dc.subject
GAG POLYPROTEIN
dc.subject
RETROVIRUS ASSEMBLY
dc.subject
RETROVIRUS BUDDING
dc.subject.classification
Virología
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dc.subject.classification
Ciencias Biológicas
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dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
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dc.title
Properties and Functions of Feline Immunodeficiency Virus Gag Domains in Virion Assembly and Budding
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-11-04T11:27:52Z
dc.journal.volume
10
dc.journal.number
5
dc.journal.pagination
1-16
dc.journal.pais
Suiza
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dc.journal.ciudad
Basilea
dc.description.fil
Fil: González, Ana Silvia. Universidad de Belgrano. Facultad de Ciencias Exactas y Naturales. Laboratorio de Virología; Argentina
dc.description.fil
Fil: Affranchino, Jose Luis. Universidad de Belgrano. Facultad de Ciencias Exactas y Naturales. Laboratorio de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Viruses
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/1999-4915/10/5/261
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3390/v10050261
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