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dc.contributor.author
Prokopez, Cintia R.  
dc.contributor.author
Vallejos, Miguel Angel  
dc.contributor.author
Farinola, Romina  
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Alberio, Germán  
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Caporusso, Gabriela B.  
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Cozzarin, Linda G.  
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Chiapella, Luciana Carla  
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Fuentes, Pamela  
dc.contributor.author
Daray, Federico Manuel  
dc.date.available
2022-10-24T12:08:48Z  
dc.date.issued
2020-11  
dc.identifier.citation
Prokopez, Cintia R.; Vallejos, Miguel Angel; Farinola, Romina; Alberio, Germán; Caporusso, Gabriela B.; et al.; The history of multiple adverse childhood experiences in patients with schizophrenia is associated with more severe symptomatology and suicidal behavior with gender-specific characteristics; Elsevier; Psychiatry Research; 293; 113411; 11-2020; 1-8  
dc.identifier.issn
0165-1781  
dc.identifier.uri
http://hdl.handle.net/11336/174488  
dc.description.abstract
The current study aims to compare the prevalence of adverse childhood experiences (ACEs) between patients with schizophrenia and non-psychiatric control group, and to analyze the association of having suffered multiple ACEs with clinical symptoms of schizophrenia and suicidal behavior. A multicenter, cross-sectional study was conducted across three facilities in Buenos Aires, Argentina. One-hundred patients with schizophrenia and 50 healthy subjects were assessed with the Adverse Childhood Experiences questionnaire (ACE-Q), the Positive and Negative Syndrome Scale (PANSS), and the Columbia-Suicide Severity Rating Scale (C-SSRS). We observed that the prevalence of at least one ACE in schizophrenic patients was almost double in comparison with the non-psychiatric control group. Multiple ACEs were associated with persistent auditory hallucinations and lower negative symptoms in both sexes. Higher frequency of death ideation and a higher number of suicide attempts were reported among women. The strength of this study is the possibility of comparing the presence of ACEs between schizophrenic patients and non-psychiatric control using the same questionnaire in an under-reported sample of low socio-economic patients assisted in public hospitals. A limitation is that the history of ACEs relied on the retrospective assessment of childhood experiences, and adults could over-report ACEs because of recall bias.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/  
dc.subject
ADVERSE CHILDHOOD EXPERIENCES  
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ADVERSE CHILDHOOD EXPERIENCES QUESTIONNAIRE  
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HALLUCINATIONS  
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SCHIZOPHRENIA  
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SUICIDAL BEHAVIOR  
dc.subject.classification
Psiquiatría  
dc.subject.classification
Medicina Clínica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
The history of multiple adverse childhood experiences in patients with schizophrenia is associated with more severe symptomatology and suicidal behavior with gender-specific characteristics  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2022-09-19T15:07:58Z  
dc.identifier.eissn
1872-7123  
dc.journal.volume
293  
dc.journal.number
113411  
dc.journal.pagination
1-8  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Amsterdam  
dc.description.fil
Fil: Prokopez, Cintia R.. Gobierno de la Ciudad Autonoma de Buenos Aires. Hospital Neuropsiquiatrico Braulio Aurelio Moyano.; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Farmacología; Argentina  
dc.description.fil
Fil: Vallejos, Miguel Angel. Gobierno de la Ciudad de Buenos Aires. Hospital Municipal "José Tiburcio Borda"; Argentina  
dc.description.fil
Fil: Farinola, Romina. Gobierno de la Ciudad de Buenos Aires. Hospital Municipal "José Tiburcio Borda"; Argentina  
dc.description.fil
Fil: Alberio, Germán. Gobierno de la Ciudad Autonoma de Buenos Aires. Hospital Neuropsiquiatrico Braulio Aurelio Moyano.; Argentina  
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Fil: Caporusso, Gabriela B.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; Argentina  
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Fil: Cozzarin, Linda G.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; Argentina  
dc.description.fil
Fil: Chiapella, Luciana Carla. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Farmacia; Argentina  
dc.description.fil
Fil: Fuentes, Pamela. Gobierno de la Ciudad Autonoma de Buenos Aires. Hospital Neuropsiquiatrico Braulio Aurelio Moyano.; Argentina  
dc.description.fil
Fil: Daray, Federico Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Farmacologia; Argentina  
dc.journal.title
Psychiatry Research  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0165178120304984  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.psychres.2020.113411