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dc.contributor.author
Alonso, Maria del Rosario
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dc.contributor.author
Anesini, Claudia Alejandra
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dc.date.available
2022-10-17T16:10:26Z
dc.date.issued
2021-07
dc.identifier.citation
Alonso, Maria del Rosario; Anesini, Claudia Alejandra; A natural product that accelerates hair growth in women with chemotherapy-induced alopecia; Biomedscis; Journal Of Biomedical Science; 4; 3; 7-2021; 1071-1080
dc.identifier.issn
2690-487X
dc.identifier.uri
http://hdl.handle.net/11336/173553
dc.description.abstract
Background Chemotherapy-induced alopecia (CIA) is an adverse effect with a negative impact on quality of life, particularly in women. A lotion containing Larrea divaricata and Coffea arabica extracts to induce hair growth is commercially available in Argentina. The objective of this work was to evaluate the capacity of the lotion, to accelerate post-chemotherapy hair growth in women. Methods Design: A prospective controlled, randomized, double-blind clinical trial was performed. Clinical Trial Registration No.: CEICYT-UAI, protocol no. 0-1026- 26/12/2017. Setting: Hospital Austral, Buenos Aires, Argentina. Participants: female patients, with ages ranging from 35 to 75 years, with diagnosis of cancer who had received the last chemotherapy cycle with drugs that cause alopecia four weeks before recruitment Measurements: The lotion or placebo were applied once a day and photographs of the lateral, occipital and coronary views were taken to determine the percentage of hair coverage at day 0, 30, 60 and 90. ResultsAfter 30 days the lotion increased 613% hair growth (p<0.05) and speed of hair appearance. The time elapsed from the initial visit to the time of appearance of a normal amount hair, was 57 ± 10 days for control patients and 39 ± 5.8 days for patients treated with lotion. No adverse events were observed. Conclusions: Results support the use of the lotion as a safe and affordable treatment that can accelerate hair growth in women with CIA.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Biomedscis
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.subject
LARREA DIVARICATA
dc.subject
COFFEA ARABICA
dc.subject
HAIR GROWTH
dc.subject.classification
Otras Ciencias de la Salud
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dc.subject.classification
Ciencias de la Salud
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
A natural product that accelerates hair growth in women with chemotherapy-induced alopecia
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-09-21T16:53:59Z
dc.journal.volume
4
dc.journal.number
3
dc.journal.pagination
1071-1080
dc.journal.pais
Estados Unidos
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dc.description.fil
Fil: Alonso, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
dc.description.fil
Fil: Anesini, Claudia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
dc.journal.title
Journal Of Biomedical Science
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://biomedscis.com/fulltext/a-natural-product-that-accelerates-hair-growth-in-women-with-chemotherapy-induced-alopecia.ID.000305.php#:~:text=ABSTRACT,is%20commercially%20available%20in%20Argentina.
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