Artículo
Nuclear-encoded mitochondrial complex I gene expression is restored to normal levels by inhibition of unedited ATP9 transgene expression in Arabidopsis thaliana
Busi, María Victoria
; Gomez Casati, Diego Fabian
; Perales, Mariano; Araya, Alejandro; Zabaleta, Eduardo Julian
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Fecha de publicación:
12/2006
Editorial:
Elsevier France-Editions Scientifiques Medicales Elsevier
Revista:
Plant Physiology and Biochemistry
ISSN:
0981-9428
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Mitochondria play an important role during sporogenesis in plants. The steady state levels of the nuclear-encoded mitochondrial complex I (nCI), PSST, TYKY and NADHBP transcripts increase in flowers of male-sterile plants with impairment of mitochondrial function generated by the expression of the unedited version of ATP9 (u-ATP9). This suggests a nuclear control of nCI genes in response to the mitochondrial flaw. To evaluate this hypothesis, transgenic plants carrying the GUS reporter gene, under the control of the PSST, TYKY and NADHBP promoters, were constructed. We present evidence that suppression by antisense strategy of the expression of u-ATP9 restores the normal levels of three nCI transcripts, indicating that the increase in PSST, TYKY and NADHBP in plants with a mitochondrial flaw occurs at the transcriptional level. The data presented here support the hypothesis that a mitochondrial dysfunction triggers a retrograde signaling which induce some nuclear-encoded mitochondrial genes. Moreover, these results demonstrate that this is a valuable experimental model for studying nucleus-mitochondria cross-talk events. © 2006 Elsevier SAS. All rights reserved.
Palabras clave:
ARABIDOPSIS
,
COMPLEX I
,
MALE STERILITY
,
MITOCHONDRIA
,
RETROGRADE REGULATION
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Identificadores
Colecciones
Articulos(IIB)
Articulos de INSTITUTO DE INVESTIGACIONES BIOLOGICAS
Articulos de INSTITUTO DE INVESTIGACIONES BIOLOGICAS
Articulos(IIB-INTECH)
Articulos de INST.DE INVEST.BIOTECNOLOGICAS - INSTITUTO TECNOLOGICO CHASCOMUS
Articulos de INST.DE INVEST.BIOTECNOLOGICAS - INSTITUTO TECNOLOGICO CHASCOMUS
Citación
Busi, María Victoria; Gomez Casati, Diego Fabian; Perales, Mariano; Araya, Alejandro; Zabaleta, Eduardo Julian; Nuclear-encoded mitochondrial complex I gene expression is restored to normal levels by inhibition of unedited ATP9 transgene expression in Arabidopsis thaliana; Elsevier France-Editions Scientifiques Medicales Elsevier; Plant Physiology and Biochemistry; 44; 1; 12-2006; 1-6
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