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Therapeutic potential of histamine H4 receptor agonists in triple-negative human breast cancer experimental model

Martinel Lamas, Diego JoséIcon ; Croci, Maximo; Carabajal, Eliana; Crescenti, Ernesto J. V.; Sambuco, Lorena Andrea; Massari, Noelia AndreaIcon ; Bergoc, Rosa Maria; Rivera, Elena Susana; Medina, Vanina AraceliIcon
Fecha de publicación: 09 - 2013
Editorial: Wiley
Revista: British Journal of Pharmacology
Idioma: Inglés
URI: http://hdl.handle.net/11336/1725
http://onlinelibrary.wiley.com/doi/10.1111/bph.12137/epdf
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764860/pdf/bph0170-0188.pdf
http://dx.doi.org/DOI:10.1111/bph.12137
Citación: Martinel Lamas, Diego José; Croci, Maximo; Carabajal, Eliana; Crescenti, Ernesto J. V.; Sambuco, Lorena Andrea; et al.; Therapeutic potential of histamine H4 receptor agonists in triple-negative human breast cancer experimental model; Wiley; British Journal of Pharmacology; 170; 1; 9-2013; 188-199

Abstract

The presence of the histamine H₄ receptor (H₄R) was previously reported in benign and malignant lesions and cell lines derived from the human mammary gland. The aim of this work was to evaluate the effects of H₄R ligands on the survival, tumour growth rate and metastatic capacity of breast cancer in an experimental model.

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