Artículo
Alterations of locomotor activity rhythm and sleep parameters in patients with advanced glaucoma
Lanzani, María Florencia; de Zavalia, Nuria Maria Asuncion
; Fontana, Héctor; Keller Sarmiento, Maria Ines
; Golombek, Diego Andres
; Rosenstein, Ruth Estela
Fecha de publicación:
08/2012
Editorial:
Taylor & Francis
Revista:
Chronobiology International
ISSN:
0742-0528
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The aim of this study was to evaluate the effect of advanced glaucoma on locomotor activity rhythms and related sleep parameters. Nine normal subjects and nine age-matched patients with bilateral advanced primary open-angle glaucoma, >10 yrs since diagnosis, were included in this observational, prospective, case-control study. Patients were required to record the timing and duration of their sleep and daily activities, and wore an actigraph on the wrist of the nondominant arm for 20 d. Activity rhythm period, MESOR (24-h time-series mean), amplitude (one-half peak-to-trough variation), and acrophase (peak time), plus long sleep episodes during the wake state, sleep duration, efficiency, and latency, as well as mean activity score, wake minutes, and mean wake episodes during the sleep interval were assessed in controls and glaucomatous patients. Glaucomatous patients exhibited significant decrease in nighttime sleep efficiency, and significant increase in the mean activity score, wake minutes, and mean wake episode during the night. These results suggest that alterations of circadian physiology could be a risk to the quality of life of patients with glaucoma.
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Articulos(CEFYBO)
Articulos de CENTRO DE ESTUDIOS FARMACOLOGICOS Y BOTANICOS
Articulos de CENTRO DE ESTUDIOS FARMACOLOGICOS Y BOTANICOS
Citación
Lanzani, María Florencia; de Zavalia, Nuria Maria Asuncion; Fontana, Héctor; Keller Sarmiento, Maria Ines; Golombek, Diego Andres; et al.; Alterations of locomotor activity rhythm and sleep parameters in patients with advanced glaucoma; Taylor & Francis; Chronobiology International; 29; 7; 8-2012; 911-919
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