Mostrar el registro sencillo del ítem
dc.contributor.author
Seimandi, Gisela Marisol
dc.contributor.author
Alvarez, Norma Hortensia
dc.contributor.author
Stegmayer, María Inés
dc.contributor.author
Fernandez, Laura Noemí
dc.contributor.author
Ruiz, Verónica Eugenia
dc.contributor.author
Favaro, María Alejandra
dc.contributor.author
Derita, Marcos Gabriel
dc.date.available
2022-09-29T14:29:10Z
dc.date.issued
2021-10
dc.identifier.citation
Seimandi, Gisela Marisol; Alvarez, Norma Hortensia; Stegmayer, María Inés; Fernandez, Laura Noemí; Ruiz, Verónica Eugenia; et al.; An Update on Phytochemicals and Pharmacological Activities of the Genus Persicaria and Polygonum; Molecular Diversity Preservation International; Molecules; 26; 19; 10-2021; 1-37
dc.identifier.issn
1420-3049
dc.identifier.uri
http://hdl.handle.net/11336/171016
dc.description.abstract
The discovery of new pharmaceutical identities, particularly anti-infective agents, rep-resents an urgent need due to the increase in immunocompromised patients and the ineffective-ness/toxicity of the drugs currently used. The scientific community has recognized in the last decades the importance of the plant kingdom as a huge source of novel molecules which could act against different type of infections or illness. However, the great diversity of plant species makes it difficult to select them with probabilities of success, adding to the fact that existing information is difficult to find, it is atomized or disordered. Persicaria and Polygonum constitute two of the main representatives of the Polygonaceae family, which have been extensively used in traditional medicine worldwide. Important and structurally diverse bioactive compounds have been isolated from these genera of wild plants; among them, sesquiterpenes and flavonoids should be remarked. In this article, we firstly mention all the species reported with pharmacological use and their geographical distribution. Moreover, a number of tables which summarize an update detailing the type of natural product (extract or isolated compound), applied doses, displayed bioassays and the results obtained for the main bioactivities of these genera cited in the literature during the past 40 years. Antimicrobial, antioxidant, analgesic and anti-inflammatory, antinociceptive, anticancer, antiviral, antiparasitic, anti-diabetic, antipyretic, hepatoprotective, diuretic, gastroprotective and neuropharmacological activities were explored and reviewed in this work, concluding that both genera could be the source for upcoming molecules to treat different human diseases.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Molecular Diversity Preservation International
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
BIOACTIVE COMPOUNDS
dc.subject
INFECTIOUS DISEASES
dc.subject
NATURAL PRODUCTS
dc.subject
PERSICARIA
dc.subject
PHARMACOLOGICAL ACTIVITIES
dc.subject
POLYGONUM
dc.subject.classification
Agronomía, reproducción y protección de plantas
dc.subject.classification
Agricultura, Silvicultura y Pesca
dc.subject.classification
CIENCIAS AGRÍCOLAS
dc.title
An Update on Phytochemicals and Pharmacological Activities of the Genus Persicaria and Polygonum
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-09-29T12:17:26Z
dc.journal.volume
26
dc.journal.number
19
dc.journal.pagination
1-37
dc.journal.pais
Suiza
dc.journal.ciudad
Basel
dc.description.fil
Fil: Seimandi, Gisela Marisol. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Instituto de Ciencias Agropecuarias del Litoral. - Universidad Nacional del Litoral. Instituto de Ciencias Agropecuarias del Litoral.; Argentina
dc.description.fil
Fil: Alvarez, Norma Hortensia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Instituto de Ciencias Agropecuarias del Litoral. - Universidad Nacional del Litoral. Instituto de Ciencias Agropecuarias del Litoral.; Argentina
dc.description.fil
Fil: Stegmayer, María Inés. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Instituto de Ciencias Agropecuarias del Litoral. - Universidad Nacional del Litoral. Instituto de Ciencias Agropecuarias del Litoral.; Argentina
dc.description.fil
Fil: Fernandez, Laura Noemí. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Instituto de Ciencias Agropecuarias del Litoral. - Universidad Nacional del Litoral. Instituto de Ciencias Agropecuarias del Litoral.; Argentina
dc.description.fil
Fil: Ruiz, Verónica Eugenia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Instituto de Ciencias Agropecuarias del Litoral. - Universidad Nacional del Litoral. Instituto de Ciencias Agropecuarias del Litoral.; Argentina
dc.description.fil
Fil: Favaro, María Alejandra. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Instituto de Ciencias Agropecuarias del Litoral. - Universidad Nacional del Litoral. Instituto de Ciencias Agropecuarias del Litoral.; Argentina
dc.description.fil
Fil: Derita, Marcos Gabriel. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Instituto de Ciencias Agropecuarias del Litoral. - Universidad Nacional del Litoral. Instituto de Ciencias Agropecuarias del Litoral.; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Química Orgánica. Área Farmacognosia; Argentina
dc.journal.title
Molecules
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3390/molecules26195956
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/1420-3049/26/19/5956
Archivos asociados