Mostrar el registro sencillo del ítem
dc.contributor.author
Blois, Sandra M.
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.contributor.author
Verlohren, Stefan
dc.contributor.author
Wu, Gang
dc.contributor.author
Clark, Gary
dc.contributor.author
Dell, Anne
dc.contributor.author
Haslam, Stuart M.
dc.contributor.author
Barrientos, Gabriela Laura
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.date.available
2022-09-23T03:15:30Z
dc.date.issued
2020-08
dc.identifier.citation
Blois, Sandra M.; Verlohren, Stefan; Wu, Gang; Clark, Gary; Dell, Anne; et al.; Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB); Springer; Seminars in Immunopathology; 42; 4; 8-2020; 469-486
dc.identifier.issn
1863-2297
dc.identifier.uri
http://hdl.handle.net/11336/170102
dc.description.abstract
Growing evidence suggests that galectins, an evolutionarily conserved family of glycan-binding proteins, fulfill key roles in pregnancy including blastocyst implantation, maternal-fetal immune tolerance, placental development, and maternal vascular expansion, thereby establishing a healthy environment for the growing fetus. In this review, we comprehensively present the function of galectins in shaping cellular circuits that characterize a healthy pregnancy. We describe the current understanding of galectins in term and preterm labor and discuss how the galectin-glycan circuits contribute to key immunological pathways sustaining maternal tolerance and preventing microbial infections. A deeper understanding of the glycoimmune pathways regulating early events in preterm birth could offer the broader translational potential for the treatment of this devastating syndrome.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Springer
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
GALECTINS
dc.subject
GLYCANS
dc.subject
MICROBIAL INFECTIONS
dc.subject
PRETERM BIRTH
dc.subject.classification
Patología
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
Medicina Básica
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.title
Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB)
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-09-22T15:09:06Z
dc.identifier.eissn
1863-2300
dc.journal.volume
42
dc.journal.number
4
dc.journal.pagination
469-486
dc.journal.pais
Alemania
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.description.fil
Fil: Blois, Sandra M.. Experimental and Clinical Research Center; Alemania. Charité-Universitätsmedizin Berlin; Alemania. University Medical Center Hamburg-Eppendorf; Alemania
dc.description.fil
Fil: Verlohren, Stefan. Charité-Universitätsmedizin Berlin; Alemania
dc.description.fil
Fil: Wu, Gang. Imperial College London; Reino Unido
dc.description.fil
Fil: Clark, Gary. University of Missouri; Estados Unidos
dc.description.fil
Fil: Dell, Anne. Imperial College London; Reino Unido
dc.description.fil
Fil: Haslam, Stuart M.. Imperial College London; Reino Unido
dc.description.fil
Fil: Barrientos, Gabriela Laura. Hospital Aleman. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Seminars in Immunopathology
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00281-020-00801-4
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s00281-020-00801-4
Archivos asociados