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dc.contributor.author
Benedini, Luciano Alejandro
dc.contributor.author
Messina, Paula Verónica
dc.date.available
2022-09-20T00:20:52Z
dc.date.issued
2021-01
dc.identifier.citation
Benedini, Luciano Alejandro; Messina, Paula Verónica; Nanodevices for Facing New Challenges of Medical Treatments: Stimuli-Responsive Drug Delivery Systems; Medknow Publications and Media Pvt. Ltd.; Systematic Reviews in Pharmacy; 12; 1; 1-2021; 1-23
dc.identifier.issn
0975-8453
dc.identifier.uri
http://hdl.handle.net/11336/169411
dc.description.abstract
The administration of therapeutic agents for the treatment of diseases without inclusion in a pharmaceutical formulation has been rarely reported in the current literature. In this condition, drugs show poor biodistribution profiles, a lack of predictable therapeutic response, and possible toxicity. For overcoming this issue, delivery systems were developed to carry, release drugs that finally interact with target sites with accuracy. The advent of nanotechnology has encouraged the improvement of these devices for facing new challenges of medical treatments. Therefore, pharmaceutical formulations have evolved from dissolutions and powders towards nanosized-smart drug delivery systems. Consequently, in this review, they are shown the main applications of nanotechnology on the design and development of drug delivery devices such as niosomes, liposomes, lipid-based nanoparticles, polymeric micelles, polymer-based devices, liquid crystals-based systems, and nanocomposites; and their capability for responding to different external and/or internal stimuli and thus release their content in the specific site. Owing to the progress in drug (or another therapeutic agent) delivery system and those applied to the imaging diagnostics, a new subarea known as theranostic, have been launched. This strategy combines the diagnosis of diseases and their treatment in a one-step procedure through the application of external stimuli to a formulation that once administrated to the body can release their content for treating and also for following the progress of the disease. For that reason, theranostic therapy has also described in this text as another example of the evolution of formulations based on nanodevices.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Medknow Publications and Media Pvt. Ltd.
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
NANOTECHNOLOGY BASED DEVICES
dc.subject
STIMULY RESPOSIVE SYSTEMS
dc.subject
THERANOSTIC THERAPY
dc.subject.classification
Nano-materiales
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Nanotecnología
dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
dc.title
Nanodevices for Facing New Challenges of Medical Treatments: Stimuli-Responsive Drug Delivery Systems
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-09-13T17:26:57Z
dc.identifier.eissn
0976-2779
dc.journal.volume
12
dc.journal.number
1
dc.journal.pagination
1-23
dc.journal.pais
India
dc.journal.ciudad
Ghatkopar Mumbai
dc.description.fil
Fil: Benedini, Luciano Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; Argentina
dc.description.fil
Fil: Messina, Paula Verónica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
dc.journal.title
Systematic Reviews in Pharmacy
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.31838/srp.2021.2.5
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sysrevpharm.org/abstract/nanodevices-for-facing-new-challenges-of-medical-treatments-stimuliresponsive-drug-delivery-systems-66940.html
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