Artículo
Modeling the growth and death of Staphylococcus aureus against Melaleuca armillaris essential oil at different ph conditions
Buldain, Daniel Cornelio
; Gortari Castillo, Lihuel
; Marchetti, Maria Laura
; Julca Lozano, Karen; Bandoni, Arnaldo Luis; Mestorino, Olga Nora
Fecha de publicación:
02/2021
Editorial:
Multidisciplinary Digital Publishing Institute
Revista:
Antibiotics
e-ISSN:
2079-6382
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Essential oils (EO) are a great antimicrobial resource against bacterial resistance in public health. Math models are useful in describing the growth, survival, and inactivation of microorganisms against antimicrobials. We evaluated the antimicrobial activity of Melaleuca armillaris EO obtained from plants placed in the province of Buenos Aires (Argentina) against Staphylococcus aureus. The minimum inhibitory and bactericidal concentrations were close and decreased, slightly acidi-fying the medium from pH 7.4 to 6.5 and 5.0. This result was also evidenced by applying a sigmoid model, where the time and EO concentration necessaries to achieve 50% of the maximum effect decreased when the medium was acidified. Moreover, at pH 7.4, applying the Gompertz model, we found that subinhibitory concentrations of EO decreased the growth rate and the maximum popu-lation density and increased the latency period concerning the control. Additionally, we established physicochemical parameters for quality control and standardization of M. armillaris EO. Mathemat-ical modeling allowed us to estimate key parameters in the behavior of S. aureus and Melaleuca ar-millaris EO at different pH. This is interesting in situations where the pH changes are relevant, such as the control of intracellular infections in public health or the development of preservatives for the food industry.
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CCT - LA PLATA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Citación
Buldain, Daniel Cornelio; Gortari Castillo, Lihuel; Marchetti, Maria Laura; Julca Lozano, Karen; Bandoni, Arnaldo Luis; et al.; Modeling the growth and death of Staphylococcus aureus against Melaleuca armillaris essential oil at different ph conditions; Multidisciplinary Digital Publishing Institute; Antibiotics; 10; 2; 2-2021; 1-14
Compartir
Altmétricas