Artículo
Next generation of nanozymes: A perspective of the challenges to match biological performance
Goya, Gerardo Fabian; Mayoral, Alvaro; Winkler, Elin Lilian
; Zysler, Roberto Daniel
; Bagnato, Carolina
; Raineri Andersen, Mariana
; Fuentes García, Jesús Antonio; Lima, Enio Junior
Fecha de publicación:
11/2021
Editorial:
American Institute of Physics
Revista:
Journal of Applied Physics
ISSN:
0021-8979
e-ISSN:
1089-7550
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Nanomaterials with enzyme-like activity have been the spotlight of scientific and technological efforts to substitute natural enzymes, not only in biological research but also for industrial manufacturing, medicine, and environment healing. Notable advancements in this field along the last years relied on to the rational design of single-atom active sites, knowledge of the underlying atomic structure, and realistic ab initio theoretical models of the electronic configuration at the active site. Thus, it is plausible that a next generation of nanozymes still to come will show even improved catalytic efficiency and substrate specificity. However, the dynamic nature of the protein cage surrounding most active sites in biological enzymes adds a flexible functionality that possess a challenge for nanozyme's mimicking of their natural counterparts. We offer a perspective about where the main strategies to improve nanozymes are headed and identify some of the big challenges faced along the road to better performance. We also outline some of the most exciting bio-inspired ideas that could potentially change this field.
Palabras clave:
NANOPARTÍCULAS
,
NANOZIMAS
,
BIORREMEDIACIÓN
,
BIOMEDICINA
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos (UE-INN - NODO BARILOCHE)
Articulos de UNIDAD EJECUTORA INSTITUTO DE NANOCIENCIA Y NANOTECNOLOGIA - NODO BARILOCHE
Articulos de UNIDAD EJECUTORA INSTITUTO DE NANOCIENCIA Y NANOTECNOLOGIA - NODO BARILOCHE
Articulos(CCT - PATAGONIA NORTE)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - PATAGONIA NORTE
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - PATAGONIA NORTE
Citación
Goya, Gerardo Fabian; Mayoral, Alvaro; Winkler, Elin Lilian; Zysler, Roberto Daniel; Bagnato, Carolina; et al.; Next generation of nanozymes: A perspective of the challenges to match biological performance; American Institute of Physics; Journal of Applied Physics; 130; 19; 11-2021; 1-24
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