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dc.contributor.author
Duhart, José Manuel
dc.contributor.author
Inami, Sho
dc.contributor.author
Koh, Kyunghee
dc.date.available
2022-09-01T13:29:08Z
dc.date.issued
2021-12
dc.identifier.citation
Duhart, José Manuel; Inami, Sho; Koh, Kyunghee; Many faces of sleep regulation: Beyond the time of day and prior wake time; Wiley Blackwell Publishing, Inc; Febs Journal; 12-2021; 1-20
dc.identifier.issn
1742-464X
dc.identifier.uri
http://hdl.handle.net/11336/167145
dc.description.abstract
The two-process model of sleep regulation posits two main processes regulating sleep: the circadian process controlled by the circadian clock and the homeostatic process that depends on the history of sleep and wakefulness. The model has provided a dominant conceptual framework for sleep research since its publication ~ 40 years ago. The time of day and prior wake time are the primary factors affecting the circadian and homeostatic processes, respectively. However, it is critical to consider other factors influencing sleep. Since sleep is incompatible with other behaviors, it is affected by the need for essential behaviors such as eating, foraging, mating, caring for offspring, and avoiding predators. Sleep is also affected by sensory inputs, sickness, increased need for memory consolidation after learning, and other factors. Here, we review multiple factors influencing sleep and discuss recent insights into the mechanisms balancing competing needs.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
CIRCADIAN CLOCK
dc.subject
MOTIVATION
dc.subject
SLEEP
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SLEEP HOMEOSTASIS
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TWO-PROCESS MODEL
dc.subject.classification
Biología
dc.subject.classification
Ciencias Biológicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Many faces of sleep regulation: Beyond the time of day and prior wake time
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-08-19T18:13:55Z
dc.identifier.eissn
1742-4658
dc.journal.pagination
1-20
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Duhart, José Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina. Thomas Jefferson University; Estados Unidos
dc.description.fil
Fil: Inami, Sho. Thomas Jefferson University; Estados Unidos
dc.description.fil
Fil: Koh, Kyunghee. Thomas Jefferson University; Estados Unidos
dc.journal.title
Febs Journal
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1111/febs.16320
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/febs.16320
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