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Artículo

Biocompatible solvents and ionic liquid-based surfactants as sustainable components to formulate environmentally friendly organized systems

Dib, NahirIcon ; Lépori, Cristian Marcelo OscarIcon ; Correa, Nestor MarianoIcon ; Silber, Juana; Falcone, Ruben DarioIcon ; García Río, Luis
Fecha de publicación: 04/2021
Editorial: MDPI AG
Revista: Polymers
ISSN: 2073-4360
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:
Físico-Química, Ciencia de los Polímeros, Electroquímica

Resumen

In this review, we deal with the formation and application of biocompatible water-in-oil microemulsions commonly known as reverse micelles (RMs). These RMs are extremely important to facilitate the dissolution of hydrophilic and hydrophobic compounds for biocompatibility in applications in drug delivery, food science, and nanomedicine. The combination of two wisely chosen types of compounds such as biocompatible non-polar solvents and ionic liquids (ILs) with amphiphilic character (surface-active ionic liquids, SAILs) can be used to generate organized systems that perfectly align with the Green Chemistry concepts. Thus, we describe the current state of SAILs (protic and aprotic) to prepare RMs using non-polar but safe solvents such as esters derived from fatty acids, among others. Moreover, the use of the biocompatible solvents as the external phase in RMs and microemulsions/nanoemulsions with the other commonly used biocompatible surfactants is detailed showing the diversity of preparations and important applications. As shown by multiple examples, the properties of the RMs can be modified by changes in the type of surfactant and/or external solvents but a key fact to note is that all these modifications generate novel systems with dissimilar properties. These interesting properties cannot be anticipated or extrapolated, and deep analysis is always required. Finally, the works presented provide valuable information about the use of biocompatible RMs, making them a green and promising alternative toward efficient and sustainable chemistry.
Palabras clave: BIOCOMPATIBLE , IONIC LIQUIDS , IPM , REVERSE MICELLES , SURFACTANT
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/166091
URL: https://www.mdpi.com/2073-4360/13/9/1378
DOI: https://doi.org/10.3390/polym13091378
Colecciones
Articulos (IDAS)
Articulos de INSTITUTO PARA EL DESARROLLO AGROINDUSTRIAL Y DE LA SALUD
Citación
Dib, Nahir; Lépori, Cristian Marcelo Oscar; Correa, Nestor Mariano; Silber, Juana; Falcone, Ruben Dario; et al.; Biocompatible solvents and ionic liquid-based surfactants as sustainable components to formulate environmentally friendly organized systems; MDPI AG; Polymers; 13; 9; 4-2021; 1378-1412
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