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dc.contributor.author
Dirchwolf, Melisa
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dc.contributor.author
Marciano, Sebastian
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dc.contributor.author
Giunta, Diego Hernan
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dc.contributor.author
Ruf, Andres E.
dc.date.available
2022-08-12T23:29:32Z
dc.date.issued
2021-04
dc.identifier.citation
Dirchwolf, Melisa; Marciano, Sebastian; Giunta, Diego Hernan; Ruf, Andres E. ; Waiting list registration and liver transplantation rates among patients with autoimmune liver disease: An 11-year trend analysis; Oat; Trends in Transplantation; 14; 4-2021; 1-7
dc.identifier.issn
1887-455X
dc.identifier.uri
http://hdl.handle.net/11336/165474
dc.description.abstract
Objectives: We aimed to analyze waiting list and liver transplantation trends for autoimmune liver disease in Argentina.Methods: We designed a population-based analysis of waitlisted or liver transplanted patients for autoimmune hepatitis, primary biliary cholangitis or primary sclerosing cholangitis between 2006-2017 in Argentina. Cumulative incidence rates of waiting list registration and liver transplantation were standardized for age and sex using the 2000 WHO standard population. Joinpoint regression analysis was used to identify changes in waiting list and liver transplantation trends.Results: Waiting list registrations for autoimmune hepatitis, primary biliary cholangitis and primary sclerosing cholangitis represented 9.66%, 5.07% and 0.85%.Wait-listing rates for autoimmune hepatitis and primary biliary cholangitis increased significantly between 2006 and 2017, with an annual percentage change of 4.9% (95% CI 0.8 to 9; p=0.01) and 5.5% (95% CI 1 to 10.2; p=0.01) respectively. Patients with autoimmune hepatitis and primary biliary cholangitis aged 40-59 years showed the highest increase in waiting list registration rates. Waiting list registration trends for primary sclerosing cholangitis remained stable: annual percentagechange 1.4% (CI 95% -2.1 to 5; p=0.4). Liver transplantation for autoimmune hepatitis, primary biliary cholangitis and primary sclerosing cholangitis represented 10.69%, 5.99% and 3.64%. Liver transplantation trends remained stable in all autoimmune liver diseases.Conclusion: Increasing trends of waiting list registration of autoimmune hepatitis and primary biliary cholangitis may respond to higher diagnosis and early referral rates to liver transplant units. Nevertheless, the growing waitlisting of patients with autoimmune end-stage liver disease underlines an unmet need for effective therapy.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Oat
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
AUTOIMMUNE LIVER DISEASE
dc.subject
WAITING LIST REGISTRATION
dc.subject
LIVER TRANSPLANTATION
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TRENDS
dc.subject.classification
Trasplantes
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dc.subject.classification
Medicina Clínica
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Waiting list registration and liver transplantation rates among patients with autoimmune liver disease: An 11-year trend analysis
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-08-11T13:00:56Z
dc.journal.volume
14
dc.journal.pagination
1-7
dc.journal.pais
Estados Unidos
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dc.description.fil
Fil: Dirchwolf, Melisa. Hospital Privado de Rosario; Argentina
dc.description.fil
Fil: Marciano, Sebastian. Hospital Italiano. Departamento de Medicina.; Argentina
dc.description.fil
Fil: Giunta, Diego Hernan. Hospital Italiano. Departamento de Medicina.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Ruf, Andres E.. Fundación para la Docencia e Investigación de las Enfermedades del Hígado; Argentina
dc.journal.title
Trends in Transplantation
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.15761/TiT.1000298
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.oatext.com/waiting-list-registration-and-liver-transplantation-rates-among-patients-with-autoimmune-liver-disease-an-11-year-trend-analysis.php
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