Artículo
Generation of a human induced pluripotent stem cell line from a familial Alzheimer's disease PSEN1 T119I patient
Isaja, Luciana
; Rodríguez Varela, Maria Soledad
; Marazita, Mariela Claudia
; Mucci, Sofia
; Itzcovich, Tatiana; Chrem Mendez, Patricio Alexis; Niikado, Matías
; Ferriol Laffouillere, Sofia Lujan
; Allegri, Ricardo Francisco
; Martinetto, Horacio Enrique
; Sevlever, Gustavo; Scassa, Maria Elida; Surace, Ezequiel Ignacio
; Romorini, Leonardo
Fecha de publicación:
05/2021
Editorial:
Elsevier
Revista:
Stem Cell Research
ISSN:
1873-5061
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Human induced pluripotent stem cells (hiPSC) line FLENIi001-A was reprogrammed from dermal fibroblasts using the lentiviral-hSTEMCCA-loxP vector. Fibroblasts were obtained from a skin biopsy of a 72-year-old Caucasian male familial Alzheimer's disease patient carrying the T119I mutation in the PSEN1 gene. PSEN1 genotype was maintained and stemness and pluripotency confirmed in the FLENIi001-A hiPSC line.
Palabras clave:
STEM CELL
,
ALZHEIMER
,
PSEN1
,
FIBROBLAST
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Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Articulos de SEDE CENTRAL
Citación
Isaja, Luciana; Rodríguez Varela, Maria Soledad; Marazita, Mariela Claudia; Mucci, Sofia; Itzcovich, Tatiana; et al.; Generation of a human induced pluripotent stem cell line from a familial Alzheimer's disease PSEN1 T119I patient; Elsevier; Stem Cell Research; 53; 5-2021; 1-4
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