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dc.contributor.author
Vazquez, Fernando Javier
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dc.contributor.author
Grande Ratti, María Florencia
dc.contributor.author
Zapiola, Maria Elena
dc.contributor.author
Giunta, Diego Hernan
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dc.contributor.author
Posadas Martinez, Maria Lourdes
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dc.date.available
2022-08-12T12:59:10Z
dc.date.issued
2021-04
dc.identifier.citation
Vazquez, Fernando Javier; Grande Ratti, María Florencia; Zapiola, Maria Elena; Giunta, Diego Hernan; Posadas Martinez, Maria Lourdes; Hospitalization for venous thromboembolic disease management: a 10 years Registry in Buenos Aires, Argentina; Springer; Journal Of Thrombosis And Thrombolysis; 52; 4; 4-2021; 1187-1194
dc.identifier.issn
0929-5305
dc.identifier.uri
http://hdl.handle.net/11336/165330
dc.description.abstract
Venous thromboembolism (VTE) is the most frequent cause of preventable mortality in hospitalized patients and the third leading cause of mortality due to vascular diseases. We aim to describe patients with VTE who required hospitalization, their clinical characteristics, management and evolution after discharge. Prospective cohort which included patients with acute and symptomatic VTE who required hospitalization in a single tertiary center for their management in a 10 years´ period (between 2006 and 2016). Patients were included at the time of VTE diagnosis; we collected baseline characteristics, risk stratification and initial therapeutic approach. They were periodically, prospectively and systematically followed up to evaluate recurrence, bleeding and/or death. Time-to-event analysis was performed for these outcomes related to evolucion after discharge. 3457 confirmed VTE episodes were included for the analysis (1985 DVT, 930 PE and 542 DVT + DVT), corresponding to 3157 patients. Most were elderly, the median age was 68 years (SD 16) with a predominance of women 57% (1955). Most frequent predisposing factors were immobility (45%), active cancer (35%), recent surgery (33%), obesity (26%), recent hospitalization (22%) and previous VTE (21%). One-fourth of pulmonary embolism had sPESI 0 points. Mortality, recurrence and bleeding rates within 30 days were 14%, 10% and 5% respectively. High proportion of VTE require hospitalization for their management, even PE with low sPESI. Mortality and complication remain elevated. We encourage the development and maintenance of more VTE registries in Latin America, to fully understand local characteristics of this disease.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Springer
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dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
BLEEDING
dc.subject
MORTALITY
dc.subject
RECURRENCE
dc.subject
REGISTRY
dc.subject
VENOUS THROMBOEMBOLIC DISEASE
dc.subject.classification
Hematología
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dc.subject.classification
Medicina Clínica
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Hospitalization for venous thromboembolic disease management: a 10 years Registry in Buenos Aires, Argentina
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-08-11T13:08:16Z
dc.journal.volume
52
dc.journal.number
4
dc.journal.pagination
1187-1194
dc.journal.pais
Alemania
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dc.journal.ciudad
Berlín
dc.description.fil
Fil: Vazquez, Fernando Javier. Hospital Italiano; Argentina
dc.description.fil
Fil: Grande Ratti, María Florencia. Hospital Italiano; Argentina
dc.description.fil
Fil: Zapiola, Maria Elena. Hospital Italiano; Argentina
dc.description.fil
Fil: Giunta, Diego Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital Italiano; Argentina
dc.description.fil
Fil: Posadas Martinez, Maria Lourdes. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital Italiano; Argentina
dc.journal.title
Journal Of Thrombosis And Thrombolysis
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007/s11239-021-02459-7
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s11239-021-02459-7
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