Mostrar el registro sencillo del ítem
dc.contributor.author
Esparsa, Cecilia Ivana
dc.contributor.author
Jalalvand, Ali R.
dc.contributor.author
Akbari, Vali
dc.contributor.author
Khodarahmi, Reza
dc.contributor.author
Goicoechea, Hector Casimiro
dc.date.available
2022-08-11T11:15:14Z
dc.date.issued
2021-10
dc.identifier.citation
Esparsa, Cecilia Ivana; Jalalvand, Ali R.; Akbari, Vali; Khodarahmi, Reza; Goicoechea, Hector Casimiro; Resolving interactions of miglitol with normal and glycated human serum albumin by multivariate methods; Academic Press Inc Elsevier Science; Analytical Biochemistry; 630; 10-2021; 1-13
dc.identifier.issn
0003-2697
dc.identifier.uri
http://hdl.handle.net/11336/165101
dc.description.abstract
This article reports results of one of our projects related to the investigation of interactions of miglitol (MIG) with normal human serum albumin (HSA) and glycated HSA (GHSA) with the help of recording spectroscopic and electrochemical data. The experimental data were analyzed by conventional and chemometric methods to extract useful information for comprehensive justifications of the interactions of the MIG with HSA and GHSA. Hard- and soft-modeling chemometric methods were used to extract quantitative and qualitative information. Then, molecular docking techniques were used to further investigation of the binding of the MIG with HSA and GHSA and the extracted results were compatible with those obtained by experimental methods. Finally, according to the binding of the BV with HSA and GHSA, second-order differential pulse voltammetric data were recorded and calibrated with three-way calibration methods for exploiting second-order advantage for determination of the GHSA in the presence of the HSA to develop a novel chemometrics assisted-electroanalytical method for diagnostic and monitoring of diabetic.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Academic Press Inc Elsevier Science
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
BINDING
dc.subject
GLYCATED HUMAN SERUM ALBUMIN
dc.subject
HUMAN SERUM ALBUMIN
dc.subject
INTERACTION
dc.subject
MIGLITOL
dc.subject.classification
Química Analítica
dc.subject.classification
Ciencias Químicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Resolving interactions of miglitol with normal and glycated human serum albumin by multivariate methods
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-08-08T15:16:04Z
dc.journal.volume
630
dc.journal.pagination
1-13
dc.journal.pais
Estados Unidos
dc.description.fil
Fil: Esparsa, Cecilia Ivana. Kermanshah University of Medical Sciences; Irán
dc.description.fil
Fil: Jalalvand, Ali R.. Kermanshah University of Medical Sciences; Irán
dc.description.fil
Fil: Akbari, Vali. Kermanshah University of Medical Sciences; Irán
dc.description.fil
Fil: Khodarahmi, Reza. Kermanshah University of Medical Sciences; Irán
dc.description.fil
Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Desarrollo Analítico y Quimiometría; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina
dc.journal.title
Analytical Biochemistry
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.ab.2021.114339
Archivos asociados