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dc.contributor.author
Galicchio, Santiago
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Espeche, Alberto Antonio
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Cersosimo, Ricardo
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Chacon, Santiago
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Gamboni, Beatriz
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Adi, Javier
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Fasulo, Lorena
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Semprino, Marcos
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Fortini, Sebastian
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Cachia, Pedro
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Caraballo, Roberto Horacio
dc.date.available
2022-08-09T11:16:57Z
dc.date.issued
2021-01
dc.identifier.citation
Galicchio, Santiago; Espeche, Alberto Antonio; Cersosimo, Ricardo; Chacon, Santiago; Gamboni, Beatriz; et al.; Self-limited epilepsy with centro-temporal spikes: A study of 46 patients with unusual clinical manifestations; Elsevier Science; Epilepsy Research; 169; 1-2021; 1-8
dc.identifier.issn
0920-1211
dc.identifier.uri
http://hdl.handle.net/11336/164678
dc.description.abstract
Purpose: We retrospectively analyzed the seizure characteristics, EEG pattern, treatment, and outcome in a series of patients with self-limited epilepsy with centrotemporal spikes (SLECTS) who presented with unusual clinical manifestations. Method: A retrospective, descriptive, multicenter study was conducted evaluating 46 patients with SLECTS who had seizures with an unusual semiology. We collected data from patients with SLECTS seen at eight Argentine centers between April 1998 and April 2018. Results: Thirteen patients (28.2 %) had seizures with affective symptoms characterized by sudden fright and autonomic disturbances and mild impairment of consciousness. Eleven patients (24.8 %) had frequent seizures characterized by unilateral facial sensorimotor symptoms, oropharyngolaryngeal manifestations, and speech arrest with sialorrhea only when awake. Seven patients (15.3 %) started with opercular epileptic status with unilateral or bilateral clonic seizures of the mouth with speech arrest and sialorrhea when awake and during sleep. Seven patients (15.3 %) had postictal Todd's paralysis after unilateral clonic seizures with facial and limb movements lasting between 60 min and 130 min. Six patients (13 %) had negative myoclonus, two in a unilateral upper limb, two in a unilateral lower limb, and the remaining two patients had frequent falls. One patient (2.1 %) had focal sensorimotor seizures characterized by unilateral numbness in the cheeks and one upper limb, additional to unilateral facial clonic seizures, speech arrest, and sialorrhea. The remaining patient (2.1 %) had sporadic focal tonic-dystonic seizures in the left upper limb only during sleep. Conclusion: In our study, we found evidence of the existence of unusual clinical cases of SLECTS with typical EEG patterns and an excellent prognosis.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
CENTRO-TEMPORAL
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EPILEPSY
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FOCAL
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SELF-LIMITED: SPIKES
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Neurología Clínica
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Self-limited epilepsy with centro-temporal spikes: A study of 46 patients with unusual clinical manifestations
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-08-04T15:31:02Z
dc.journal.volume
169
dc.journal.pagination
1-8
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Galicchio, Santiago. Hospital de Niños Victor J Vilela de Rosario; México
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Fil: Espeche, Alberto Antonio. Gobierno de la Provincia de Salta. Hospital Publico Materno Infantil.; Argentina
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Fil: Cersosimo, Ricardo. Centro Integral de Neurociencias; Argentina
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Fil: Chacon, Santiago. Hospital de Niños Victor J Vilela de Rosario; Argentina
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Fil: Gamboni, Beatriz. Hospital Pediátrico Humberto H Notti de Mendoza; Argentina
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Fil: Adi, Javier. Gobierno de la Provincia de Mendoza. Hospital Pediátrico Humberto Notti; Argentina
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Fil: Fasulo, Lorena. Centro Integral de Neurociencias; Argentina. Hospital de Niños Victor J Vilela de Rosario; México. Gobierno de la Provincia de Salta. Hospital Publico Materno Infantil.; Argentina. Provincia de Tucuman. Ministerio de Salud. Sistema Provincial de Salud. Hospital del Ni?o Jesus; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
dc.description.fil
Fil: Semprino, Marcos. Centro Integral de Neurociencias; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina. Hospital de Niños Victor J Vilela de Rosario; Argentina. Gobierno de la Provincia de Salta. Hospital Publico Materno Infantil.; Argentina. Provincia de Tucuman. Ministerio de Salud. Sistema Provincial de Salud. Hospital del Ni?o Jesus; Argentina
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Fil: Fortini, Sebastian. Provincia de Tucuman. Ministerio de Salud. Sistema Provincial de Salud. Hospital del Ni?o Jesus; Argentina
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Fil: Cachia, Pedro. Hospital de Niños Victor J Vilela de Rosario; México
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Fil: Caraballo, Roberto Horacio. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Epilepsy Research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.eplepsyres.2020.106507
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