Invasive pulmonary aspergillosis and candidiasis in a critically ill patient with COVID-19

Abstract

Invasive fungal superinfections have been increasingly reported in critically ill patients with coronavirus disease-2019 (COVID-2019) due to the severe immunomodulation and lymphocyte depletion caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the subsequent administration of drugs that target the immune system such as corticosteroids. Among them, pulmonary aspergillosis and invasive candidiasis or candidemia have been widely reported . We herein describe one of the first cases in Argentina of combined probable pulmonary aspergillosis and candidemia) in a previously immunocompetent, critically ill patient with severe COVID-19 pneumonia.