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dc.contributor.author Caracciolo, Pablo Christian
dc.contributor.author Buffa, Juan Manuel
dc.contributor.author Thomas, Vinoy
dc.contributor.author Vohra, Yogesh K.
dc.contributor.author Abraham, Gustavo Abel
dc.date.available 2017-05-05T17:45:32Z
dc.date.issued 2011-09
dc.identifier.citation Caracciolo, Pablo Christian; Buffa, Juan Manuel; Thomas, Vinoy; Vohra, Yogesh K.; Abraham, Gustavo Abel; Biodegradable polyurethanes: Comparative study of electrospun scaffolds and films; Wiley; Journal Of Applied Polymer Science; 121; 6; 9-2011; 3292-3299
dc.identifier.issn 0021-8995
dc.identifier.uri http://hdl.handle.net/11336/16030
dc.description.abstract The development of elastomeric bioresorbable and biocompatible segmented polyurethanes (SPU) for use in tissue engineering applications has been a subject of considerable interest in recent years. In this work, non-porous films and micro/nanofibrous scaffolds prepared from two different poly(ε-caprolactone)-based SPU previously synthesized using 1,6-hexamethylene diisocyanate and novel chain extenders containing urea groups or an aromatic aminoacid derivative, were studied. Thermal properties were influenced both by the different chemical structure of the hard segments and the processing conditions. Mechanical properties of the scaffolds showed elastic moludus, ultimate strain and tensile stress values adecuate for soft-tissue engineered constructs (i.e.: myocardial tissue). Film samples displayed low swelling degree (less than 2 wt %) in phosphate-buffered solution (PBS) at 37 ºC. The introduction of the aminoacid derivative chain extender with hydrolyzable ester bonds contributed to a higher degradation. Fibrous scaffolds exhibited higher hydrolytic stability than films at short times of assay, due to their more crystalline structures and higher degrees of association by hydrogen bonding, but also higher mass loss values in accelerated conditions (70 ºC), suggesting that degradation rate is not constant but depends on the degradation time and the processing technique.
dc.format application/pdf
dc.language.iso eng
dc.publisher Wiley
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject NANOFIBERS
dc.subject SCAFFOLD
dc.subject THERMAL PROPERTIES
dc.subject MECHANICAL PROPERTIES
dc.subject DEGRADATION
dc.subject POLYURETHANES
dc.subject.classification Otras Ingeniería de los Materiales
dc.subject.classification Ingeniería de los Materiales
dc.subject.classification INGENIERÍAS Y TECNOLOGÍAS
dc.subject.classification Bioproductos, Biomateriales, Bioplásticos, Biocombustibles, Bioderivados, etc.
dc.subject.classification Biotecnología Industrial
dc.subject.classification INGENIERÍAS Y TECNOLOGÍAS
dc.title Biodegradable polyurethanes: Comparative study of electrospun scaffolds and films
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2017-02-06T14:30:04Z
dc.journal.volume 121
dc.journal.number 6
dc.journal.pagination 3292-3299
dc.journal.pais Estados Unidos
dc.journal.ciudad Hoboken
dc.description.fil Fil: Caracciolo, Pablo Christian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones En Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones En Ciencia y Tecnología de Materiales; Argentina
dc.description.fil Fil: Buffa, Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones En Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones En Ciencia y Tecnología de Materiales; Argentina
dc.description.fil Fil: Thomas, Vinoy. University Of Alabama At Birmingahm; Estados Unidos
dc.description.fil Fil: Vohra, Yogesh K.. University Of Alabama At Birmingahm; Estados Unidos
dc.description.fil Fil: Abraham, Gustavo Abel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones En Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones En Ciencia y Tecnología de Materiales; Argentina
dc.journal.title Journal Of Applied Polymer Science
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/app.33855/abstract?userIsAuthenticated=false&deniedAccessCustomisedMessage=
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/app.33855


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    Articulos de INST.DE INV.EN CIENCIA Y TECNOL.MATERIALES (I)

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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)