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dc.contributor.author
Filippa, Veronica Palmira
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dc.contributor.author
Penissi, Alicia Beatriz
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dc.contributor.author
Mohamed, Fabian Heber
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dc.date.available
2022-06-13T16:57:03Z
dc.date.issued
2005-12
dc.identifier.citation
Filippa, Veronica Palmira; Penissi, Alicia Beatriz; Mohamed, Fabian Heber; Seasonal variations of gonadotropins in the pars distalis male viscacha pituitary: Effect of chronic melatonin treatment; Società Italiana di Istochimica; European Journal of Histochemistry; 49; 3; 12-2005; 291-300
dc.identifier.issn
1121-760X
dc.identifier.uri
http://hdl.handle.net/11336/159582
dc.description.abstract
The gonadotropes, LH and FSH cells, were immunohistochemically identified in the pituitary pars distalis of the adult male viscacha (Lagostomus maximus maximus) using specific antibodies against hLHb and hFSHb with the streptavidin-biotin-peroxidase complex. The distribution, size and percentage immunopositive area of these cells were analyzed by image analysis in viscachas captured during the annual reproductive cycle and after the chronic administration of melatonin. The LHb and FSHb cells showed seasonal changes in the distribution, size and percentage immunopositive area. The LHb cells were found widely distributed throughout the pars distalis during the reproductive period, and they were found in the ventro-medial region in the pars distalis during the gonadal regression and gonadal recovery periods. The LHb cells reached the largest size and immunopositive area during the reproductive period and the smallest size and immunopositive area during the gonadal regression period. The FSHb cells were found in the ventromedial region during reproductive and gonadal regression periods. The FSHb cells were found widely distributed throughout the pars distalis during the gonadal recovery period when they showed the maximum percentage immunopositive area. A decrease in the size of LHb and FSHb cells was observed after the chronic administration of melatonin. Moreover, it produces a decrease in the immunopositive area occupied by the LHb cells but not in the immunopositive area occupied by the FSHb cells. Our results show great activity of LHb and FSHb cells in different moments of the annual reproductive cycle demonstrating that these cells do not secrete in parallel. Moreover, melatonin acts differentially on the activity of the gonadotrope cells.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Società Italiana di Istochimica
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
PITUITARY
dc.subject
LH
dc.subject
FSH
dc.subject
IMMUNOHISTOCHEMISTRY
dc.subject
VISCACHA
dc.subject.classification
Bioquímica y Biología Molecular
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dc.subject.classification
Ciencias Biológicas
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dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
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dc.title
Seasonal variations of gonadotropins in the pars distalis male viscacha pituitary: Effect of chronic melatonin treatment
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-06-09T13:36:22Z
dc.identifier.eissn
2038-8306
dc.journal.volume
49
dc.journal.number
3
dc.journal.pagination
291-300
dc.journal.pais
Italia
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dc.journal.ciudad
Pavia
dc.description.fil
Fil: Filippa, Veronica Palmira. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
dc.description.fil
Fil: Penissi, Alicia Beatriz. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Mendoza. Instituto de Histologia y Embriologia de Mendoza Dr. Mario H. Burgos. Grupo Vinculado de Investigacion y Desarrollo Biotecnologico Aplicado Al Diagnostico Al Ihem | Universidad Nacional de Cuyo. Facultad de Ciencias Medicas. Instituto de Histologia y Embriologia de Mendoza Dr. Mario H. Burgos. Grupo Vinculado de Investigacion y Desarrollo Biotecnologico Aplicado Al Diagnostico Al Ihem.; Argentina
dc.description.fil
Fil: Mohamed, Fabian Heber. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina
dc.journal.title
European Journal of Histochemistry
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.ejh.it/index.php/ejh/article/view/956
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.4081/956
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