Artículo
The Role of Androgen Signaling in Male Sexual Development at Puberty
Fecha de publicación:
02/2021
Editorial:
Oxford University Press
Revista:
Endocrinology
ISSN:
1945-7170
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Puberty is characterized by major changes in the anatomy and function of reproductive organs. Androgen activity is low before puberty, but during pubertal development, the testes resume the production of androgens. Major physiological changes occur in the testicular cell compartments in response to the increase in intratesticular testosterone concentrations and androgen receptor expression. Androgen activity also impacts on the internal and external genitalia. In target cells, androgens signal through a classical and a nonclassical pathway. This review addresses the most recent advances in the knowledge of the role of androgen signaling in postnatal male sexual development, with a special emphasis on human puberty.
Palabras clave:
AMH
,
ANDROGEN RECEPTOR
,
LEYDIG
,
SERTOLI
,
TESTIS
,
TRANSCRIPTIONAL REGULATION
Archivos asociados
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Identificadores
Colecciones
Articulos(CEDIE)
Articulos de CENTRO DE INVESTIGACIONES ENDOCRINOLOGICAS "DR. CESAR BERGADA"
Articulos de CENTRO DE INVESTIGACIONES ENDOCRINOLOGICAS "DR. CESAR BERGADA"
Citación
Rey, Rodolfo Alberto; The Role of Androgen Signaling in Male Sexual Development at Puberty; Oxford University Press; Endocrinology; 162; 2; 2-2021; 1-16
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