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dc.contributor.author
Filippa, Veronica Palmira
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dc.contributor.author
Mohamed, Fabian Heber
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dc.date.available
2022-05-27T19:39:30Z
dc.date.issued
2007-04
dc.identifier.citation
Filippa, Veronica Palmira; Mohamed, Fabian Heber; Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity; Karger; Cells Tissues Organs; 184; 3-4; 4-2007; 188-197
dc.identifier.issn
1422-6405
dc.identifier.uri
http://hdl.handle.net/11336/158402
dc.description.abstract
Somatotrophs were identified and quantified in pituitary pars distalis of male viscachas (Lagostomus maximus maximus) during the annual reproductive cycle, after the administration of melatonin, after castration and in different growth stages by immunohistochemistry and morphometric analysis. In adult male viscachas, the somatotrophs were distributed throughout the pars distalis during the reproductive cycle. They were oval, pyramidal or round in shape with a large round nucleus. The percentage immunopositive area, the major cellular diameter and the number of cells decreased during the gonadal regression period in relation to the values found in the reproductive period. The administration of melatonin did not provoke any variations of the morphometric parameters studied. On the contrary, a significant decrease in the percentage immunopositive area, in the major cellular diameter and in the number of somatotrophs in castrated viscachas was observed. The study of different growth stages showed that these morphometric parameters increased from immature to adult animals in the reproductive period. The results obtained suggested that the variations of the morphometric parameters of somatotrophs are more related to the gonadal development and activity than to a direct effect of melatonin.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Karger
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
LAGOSTOMUS
dc.subject
PITUITARY
dc.subject
SOMATOTROPHS
dc.subject
GONADAL
dc.subject.classification
Bioquímica y Biología Molecular
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dc.subject.classification
Ciencias Biológicas
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dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
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dc.title
Immunohistochemical Study of Somatotrophs in Pituitary Pars Distalis of Male Viscacha (Lagostomus maximus maximus) in Relation to the Gonadal Activity
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-05-20T15:06:43Z
dc.journal.volume
184
dc.journal.number
3-4
dc.journal.pagination
188-197
dc.journal.pais
Suiza
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dc.journal.ciudad
Basilea
dc.description.fil
Fil: Filippa, Veronica Palmira. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina
dc.description.fil
Fil: Mohamed, Fabian Heber. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; Argentina
dc.journal.title
Cells Tissues Organs
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1159/000099626
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/99626
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