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dc.contributor.author
Fantilli, Anabella Clara
dc.contributor.author
López Villa, Sarah Daniela
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Zerega, Alina
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Di Cola Bucciarelli, Guadalupe
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López, Luis
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Wassaf Martínez, Maribel
dc.contributor.author
Pisano, María Belén
dc.contributor.author
Ré, Viviana Elizabeth
dc.date.available
2022-05-23T23:14:09Z
dc.date.issued
2021-12
dc.identifier.citation
Fantilli, Anabella Clara; López Villa, Sarah Daniela; Zerega, Alina; Di Cola Bucciarelli, Guadalupe; López, Luis; et al.; Hepatitis E virus infection in a patient with alcohol related chronic liver disease: a case report of acute-on-chronic liver failure; BioMed Central; Virology Journal; 18; 1; 12-2021; 1-6
dc.identifier.issn
1743-422X
dc.identifier.uri
http://hdl.handle.net/11336/158066
dc.description.abstract
Background: The hepatitis E virus (HEV) infection has been described as a causing factor for acute-on-chronic-liverfailure (ACLF) in patients with underlying chronic liver disease (CLD), such as chronic hepatitis or cirrhosis, which could end in the failure of one or more organs and high short-term mortality. There are scarce data about the association of HEV in patients with chronic liver disorders in South America.
Case presentation: A 56-year-old hypertensive male with a history of type 2 diabetes was diagnosed with alcoholrelated-liver cirrhosis in February 2019. A year later, the patient was admitted to hospital due to fatigue, jaundice and acholia. No evidence of hepatitis A virus, hepatitis B virus, hepatitis C virus, Epstein–Barr virus, herpes zoster virus and cytomegalovirus infections were found. Nevertheless, in February and March, 2020 the patient was positive for HEVIgM and HEV-IgG, and HEV genotype 3 RNA was detected in sera. Afterwards, he presented grade I hepatic encephalopathy and, therefore, was diagnosed with acute hepatitis E-on-chronic liver disease. The patient reported a recent travel to the Argentine coast, where he consumed seafood. Besides, he reveled to have consumed pork meat and had no history of blood transfusion.
Conclusion: This report describes a unique case of hepatitis E virus infection in a patient with alcohol-related cirrhosis. This is the frst report of a patient with HEV-related ACLF in Argentina and it invokes the importance of HEV surveillance and treatment among patients with CLD, such as alcohol-related cirrhosis.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
BioMed Central
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
ACUTE-ON-CHRONIC HEPATITIS
dc.subject
ARGENTINA
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CHRONIC LIVER DISEASE
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CIRRHOSIS
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HEV
dc.subject.classification
Enfermedades Infecciosas
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Hepatitis E virus infection in a patient with alcohol related chronic liver disease: a case report of acute-on-chronic liver failure
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-05-12T16:49:39Z
dc.identifier.eissn
1743-422X
dc.journal.volume
18
dc.journal.number
1
dc.journal.pagination
1-6
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Fantilli, Anabella Clara. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
dc.description.fil
Fil: López Villa, Sarah Daniela. Instituto Modelo de Cardiología; Argentina
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Fil: Zerega, Alina. Sanatorio Allende; Argentina
dc.description.fil
Fil: Di Cola Bucciarelli, Guadalupe. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
dc.description.fil
Fil: López, Luis. Instituto Modelo de Cardiología; Argentina
dc.description.fil
Fil: Wassaf Martínez, Maribel. LACE Laboratorios; Argentina
dc.description.fil
Fil: Pisano, María Belén. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
dc.description.fil
Fil: Ré, Viviana Elizabeth. Universidad Nacional de Córdoba. Facultad de Medicina. Instituto de Virología Dr. J. M. Vanella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
dc.journal.title
Virology Journal
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://virologyj.biomedcentral.com/articles/10.1186/s12985-021-01714-w
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1186/s12985-021-01714-w
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