Artículo

New Dammarane Triterpenes from the aerial parts of Ibicella lutea grown in Argentina

Simirgiotis, Mario JuanIcon ; Jiménez, Carlos; Rodríguez, Jaime; Giordano, Oscar SantiagoIcon ; Tonn, Carlos EugenioIcon
Fecha de publicación: 03/12/2003
Editorial: American Chemical Society
Revista: Journal of Natural Products
ISSN: 0163-3864
e-ISSN: 1520-6025
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Two new dammarane triterpenes have been isolated from the aerial parts of Ibicella lutea, 3-acetyl-24- epi-polacandrin (1) and 1,3-diacetyl-24-epi-polacandrin (2), and were obtained along with the known compounds 20S*,24S*-epoxy-3â,12â,25-trihydroxydammarane (3) and apigenin. The structures of compounds 1 and 2 were deduced by spectroscopic studies and by chemical transformations leading to the preparation of derivatives 4-11. The structure and relative stereochemistry of 1 were verified by single-crystal X-ray analysis. The natural compounds and selected semisynthetic derivatives were evaluated against several tumor cells.
Palabras clave: Cytotoxicity , Triterpenes , Isolation , Chemical modifications
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/156907
URL: https://pubs.acs.org/doi/10.1021/np030273i
DOI: https://doi.org/10.1021/np030273i
Colecciones
Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Citación
Simirgiotis, Mario Juan; Jiménez, Carlos; Rodríguez, Jaime; Giordano, Oscar Santiago; Tonn, Carlos Eugenio; New Dammarane Triterpenes from the aerial parts of Ibicella lutea grown in Argentina; American Chemical Society; Journal of Natural Products; 66; 12; 03-12-2003; 1586-1592
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