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dc.contributor.author
Perez Damonte, Silvia
dc.contributor.author
Moyano, Maria Alejandra
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dc.contributor.author
Nuñez, Myriam Carmen
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dc.contributor.author
Segall, Adriana Ines
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dc.date.available
2022-05-06T18:10:34Z
dc.date.issued
2021-05
dc.identifier.citation
Perez Damonte, Silvia; Moyano, Maria Alejandra; Nuñez, Myriam Carmen; Segall, Adriana Ines; Effects of α-lipoic acid on the biomechanical properties of the skin; GSC Online Press; World Journal of Advanced Research and Reviews; 10; 2; 5-2021; 057-070
dc.identifier.uri
http://hdl.handle.net/11336/156832
dc.description.abstract
Abstract Background: The Cutometer MPA 580® (Courage and Khazaka, Germany) is a well-established instrument for the accurate and reproducible measurement of the biomechanical properties of the skin. The purpose of this study was to assess the effect of 4 formulations containing 2.5% and 5.0% of α-lipoic acid and ascorbic palmitate or butylhydroxytoluene on skin elasticity and firmness and to assess the equivalence between alternative parameters (Q0, Q1 and Q3) and the traditional parameters R0, R2, R5, R6, all determined with the same cutometer. Methods: Measure of in vivo firmness and elasticity of the skin was performed using R and Q parameters measured in the same device. Results: Different statistical analysis were applied to the results obtained from the parameters (Q0, Q1 and Q3) and the traditional parameters R0, R2, of the in vivo measurements after the application of the four formulations during 28 days. A correlation between both types of measurements was demonstrate. Conclusion: A four-week treatment with a cream containing 5% α-lipoic acid improves the biomechanical characteristics of the skin, thus contributing to the protection against photo-aging. Both methods of measurement proved to be equivalent.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
GSC Online Press
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
Alpha lipoc acid
dc.subject
Cutometer
dc.subject
Firmness
dc.subject
Elasticity
dc.subject.classification
Otras Ciencias Médicas
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dc.subject.classification
Otras Ciencias Médicas
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Effects of α-lipoic acid on the biomechanical properties of the skin
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2022-04-21T16:25:55Z
dc.identifier.eissn
2581-9615
dc.journal.volume
10
dc.journal.number
2
dc.journal.pagination
057-070
dc.journal.pais
India
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dc.journal.ciudad
Maharashtra
dc.description.fil
Fil: Perez Damonte, Silvia. CLAIM; Argentina
dc.description.fil
Fil: Moyano, Maria Alejandra. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Laboratorio de Control de Calidad de Medicamentos; Argentina
dc.description.fil
Fil: Nuñez, Myriam Carmen. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Físico Matemática; Argentina
dc.description.fil
Fil: Segall, Adriana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Laboratorio de Control de Calidad de Medicamentos; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Tecnología Farmacéutica; Argentina
dc.journal.title
World Journal of Advanced Research and Reviews
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://wjarr.com/content/effects-alpha-lipoic-acid-biomechanical-properties-skin
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.30574/wjarr.2021.10.2.0169
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