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dc.contributor.author
Gomez, Ricardo Martin
dc.contributor.author
López Ortiz, Aída Oryza
dc.contributor.author
Schattner, Mirta Ana
dc.date.available
2022-04-06T20:03:25Z
dc.date.issued
2020-01-26
dc.identifier.citation
Gomez, Ricardo Martin; López Ortiz, Aída Oryza; Schattner, Mirta Ana; Platelets and extracellular traps in infections; Taylor & Francis Ltd; Platelets; 32; 3; 26-1-2020; 1-9
dc.identifier.issn
0953-7104
dc.identifier.uri
http://hdl.handle.net/11336/154549
dc.description.abstract
Platelets have a well-recognized role in hemostasis and thrombosis, and they are important amplifiers of inflammation and innate immune responses. The formation of DNA extracellular traps (ETs) is a complex cellular mechanism, which occurs in response to microbial infections and sterile inflammation, and results in the release of DNA complexed with histones and various granular proteins. ETs were first discovered in neutrophils (NETs); however, it is now accepted that other leukocytes, including eosinophils (EETs) and monocytes/macrophages (MoETs/METs), can also generate them. Moreover, several types of ETs have been described. Increasing evidence has demonstrated that platelets modulate the formation of ETs. This review summarizes recent findings about the physiopathological role of platelets in the formation of ETs during infection and future perspectives in the field.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Taylor & Francis Ltd
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
BACTERIA
dc.subject
EXTRACELLULAR TRAPS
dc.subject
INFECTIONS
dc.subject
MACROPHAGES
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NEUTROPHILS
dc.subject
PLATELETS
dc.subject
VIRUS
dc.subject.classification
Inmunología
dc.subject.classification
Medicina Básica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Platelets and extracellular traps in infections
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2021-09-06T17:50:44Z
dc.identifier.eissn
1369-1635
dc.journal.volume
32
dc.journal.number
3
dc.journal.pagination
1-9
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Gomez, Ricardo Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Biotecnología y Biología Molecular. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología y Biología Molecular; Argentina
dc.description.fil
Fil: López Ortiz, Aída Oryza. Universidad Nacional de La Plata; Argentina
dc.description.fil
Fil: Schattner, Mirta Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
dc.journal.title
Platelets
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/09537104.2020.1718631
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1080/09537104.2020.1718631
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