Artículo
The Role of Galectin-3 and ST2 in Cardiology: A Short Review
Merino, Ana; González Bernal, Jerónimo; Fernández, Darío
; Saez Maleta, Ruth; Pérez Rivera, José Ángel
Fecha de publicación:
08/2021
Editorial:
Molecular Diversity Preservation International
Revista:
Biomolecules
ISSN:
2218-273X
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Galectin-3 is a lectin that binds beta-galactosides. It is involved in cardiac remodeling and fibrosis through the activation of macrophages and fibroblasts. ST2 is secreted by myocardial cells due to cardiac overload. These two biomarkers have been traditionally studied in the field of heart failure to guide medical therapy and detect the progression of the disease. Nevertheless, there are novel evidences that connect galectin-3 and ST2 with coronary heart disease and, specifically, with atrial fibrillation. The aim of this article is to concisely review the diagnostic and prognostic role of galectin-3 and ST2 in different cardiac diseases.
Palabras clave:
BIOMARKERS
,
CARDIOLOGY
,
GALECTIN-3
,
ST2
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CCT - NORDESTE)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - NORDESTE
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - NORDESTE
Citación
Merino, Ana; González Bernal, Jerónimo; Fernández, Darío; Saez Maleta, Ruth; Pérez Rivera, José Ángel; The Role of Galectin-3 and ST2 in Cardiology: A Short Review; Molecular Diversity Preservation International; Biomolecules; 11; 8; 8-2021; 1-9
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