Mostrar el registro sencillo del ítem

dc.contributor.author
Castells, Matías  
dc.contributor.author
Caffarena, Rubén Darío  
dc.contributor.author
Casaux, María Laura  
dc.contributor.author
Schild, Carlos  
dc.contributor.author
Miño, Samue  
dc.contributor.author
Castells, Felipe  
dc.contributor.author
Castells, Daniel  
dc.contributor.author
Victoria, Matías  
dc.contributor.author
Riet Correa, Franklin  
dc.contributor.author
Giannitti, Federico  
dc.contributor.author
Parreño, Gladys Viviana  
dc.contributor.author
Colina, Rodney  
dc.date.available
2022-01-27T10:40:05Z  
dc.date.issued
2020-07  
dc.identifier.citation
Castells, Matías; Caffarena, Rubén Darío; Casaux, María Laura; Schild, Carlos; Miño, Samue; et al.; Phylogenetic analyses of rotavirus a from cattle in uruguay reveal the circulation of common and uncommon genotypes and suggest interspecies transmission; Molecular Diversity Preservation International; Pathogens; 9; 7; 7-2020; 1-17  
dc.identifier.issn
2076-0817  
dc.identifier.uri
http://hdl.handle.net/11336/150783  
dc.description.abstract
Uruguay is one of the main exporters of beef and dairy products, and cattle production is one of the main economic sectors in this country. Rotavirus A (RVA) is the main pathogen associated with neonatal calf diarrhea (NCD), a syndrome that leads to significant economic losses to the livestock industry. The aims of this study are to determine the frequency of RVA infections, and to analyze the genetic diversity of RVA strains in calves in Uruguay. A total of 833 samples from dairy and beef calves were analyzed through RT-qPCR and sequencing. RVA was detected in 57.0% of the samples. The frequency of detection was significantly higher in dairy (59.5%) than beef (28.4%) calves (p < 0.001), while it did not differ significantly among calves born in herds that were vaccinated (64.0%) or not vaccinated (66.7%) against NCD. The frequency of RVA detection and the viral load were significantly higher in samples from diarrheic (72.1%, 7.99 log10 genome copies/mL of feces) than non-diarrheic (59.9%, 7.35 log10 genome copies/mL of feces) calves (p < 0.005 and p = 0.007, respectively). The observed G-types (VP7) were G6 (77.6%), G10 (20.7%), and G24 (1.7%), while the P-types were P[5] (28.4%), P[11] (70.7%), and P[33] (0.9%). The G-type and P-type combinations were G6P[11] (40.4%), G6P[5] (38.6%), G10P[11] (19.3%), and the uncommon genotype G24P[33] (1.8%). VP6 and NSP1-5 genotyping were performed to better characterize some strains. The phylogenetic analyses suggested interspecies transmission, including transmission between animals and humans.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Molecular Diversity Preservation International  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
BOVINE  
dc.subject
DIARRHEA  
dc.subject
GENOTYPES  
dc.subject
INTERSPECIES TRANSMISSION  
dc.subject
ROTAVIRUS  
dc.subject.classification
Otras Ciencias Veterinarias  
dc.subject.classification
Ciencias Veterinarias  
dc.subject.classification
CIENCIAS AGRÍCOLAS  
dc.title
Phylogenetic analyses of rotavirus a from cattle in uruguay reveal the circulation of common and uncommon genotypes and suggest interspecies transmission  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2021-09-07T15:15:00Z  
dc.journal.volume
9  
dc.journal.number
7  
dc.journal.pagination
1-17  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
New York  
dc.description.fil
Fil: Castells, Matías. Universidad de la República; Uruguay  
dc.description.fil
Fil: Caffarena, Rubén Darío. Universidad de la República; Uruguay  
dc.description.fil
Fil: Casaux, María Laura. Universidad de la República; Uruguay  
dc.description.fil
Fil: Schild, Carlos. Universidad de la República; Uruguay  
dc.description.fil
Fil: Miño, Samue. Instituto Nacional de Tecnología Agropecuaria; Argentina  
dc.description.fil
Fil: Castells, Felipe. Universidad de la República; Uruguay  
dc.description.fil
Fil: Castells, Daniel. Universidad de la República; Uruguay  
dc.description.fil
Fil: Victoria, Matías. Universidad de la República; Uruguay  
dc.description.fil
Fil: Riet Correa, Franklin. Universidad de la República; Uruguay  
dc.description.fil
Fil: Giannitti, Federico. Universidad de la República; Uruguay  
dc.description.fil
Fil: Parreño, Gladys Viviana. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Virología E Innovaciones Tecnológicas. - Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Pque. Centenario. Instituto de Virología E Innovaciones Tecnológicas; Argentina  
dc.description.fil
Fil: Colina, Rodney. Universidad de la República; Uruguay  
dc.journal.title
Pathogens  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3390/pathogens9070570