What are the benefits and harms of aspirin 1000 mg for adults with episodic tension-type headache?

Abstract

For adults with episodic tension‐type headache, low‐certainty evidence suggests that, compared with placebo, aspirin 1000 mg may result in less need for rescue medication (on average, 158 vs 339 per 1000 people), with no apparent impact on adverse events. For the other outcomes, event rates were low and certainty of evidence was very low, precluding any conclusions.